Osteoarthritis among elderly: cross-sectional study of hospitalization between 2010 and 2022
INTRODUCTION: Osteoarthritis is a common joint disease and one of the main causes of years lived with disabilities as well as one of the reasons for visits to health services.
Aranzazu Cueva-G.Cantón +3 more
doaj +1 more source
Causal Effect Inference with Deep Latent-Variable Models [PDF]
Learning individual-level causal effects from observational data, such as inferring the most effective medication for a specific patient, is a problem of growing importance for policy makers.
Louizos, Christos +5 more
core +1 more source
A Detailed Observational Study of Molecular Loops 1 and 2 in the Galactic Center
Fukui et al. (2006) discovered two huge molecular loops in the Galactic center located in (l, b) ~ (355 deg-359 deg, 0 deg-2 deg) in a large velocity range of -180-40 km s^-1.
Fujishita, Motosuji +13 more
core +3 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Phenotyping adults with non-cystic fibrosis bronchiectasis: A prospective observational cohort study [PDF]
Ghazanfar Ali Anwar +10 more
openalex +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Laurent Portel,1 Caroline Fabry-Vendrand,2 Nathalie Texier,3 Déborah Schwartz,3 Audrey Capdepon,2 Gabriel Thabut,2 Didier Debieuvre4 1Service de Pneumologie, Centre Hospitalier Robert Boulin, Libourne, France; 2Astra Zeneca, Courbevoie, France ...
Portel L +6 more
doaj
Observational study of hydrocarbons in the bright photodissociation region of Messier 8
Hydrocarbons are ubiquitous in the interstellar medium, but their formation is still not well understood, depending on the physical environment they are found in. M8 is host to one of the brightest HII regions and PDRs in our galaxy.
Kim, W. -J. +5 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Clinical specialty training in UK undergraduate medical schools: A retrospective observational study [PDF]
Objectives: To determine if increased exposure to clinical specialties at medical school is associated with increased interest in pursuing that specialty as a career after foundation training. Design: A retrospective observational study.
Alexander, Emma C +5 more
core +1 more source

