Results 71 to 80 of about 397,857 (258)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Generalized H2 observer for road profile estimation in the automotive suspension system
HeliyonThis study develops a generalized H2 observer to estimate the road profile in the semi-active automotive suspension system. The dynamics of the quarter-car model are represented in the descriptor nonlinear parameter-varying system framework, with the ...
Thanh-Phong Pham
doaj +1 more source
Proprioceptive Sensors’ Fault Tolerant Control Strategy for an Autonomous Vehicle
Sensors, 2018 In this contribution, a fault-tolerant control strategy for the longitudinal dynamics of an autonomous vehicle is presented. The aim is to be able to detect potential failures of the vehicle’s speed sensor and then to keep the vehicle in a safe state ...
Mohamed Riad Boukhari +3 more
doaj +1 more source
Control of flexible joint robotic manipulator using tuning functions design
, 1999 The goal of this thesis is to design the controller for a single arm manipulator having a flexible joint for the tracking problem in two different cases.
Aripirala Venkata, Pavan Krishna
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Journal of Marine Science and EngineeringThis article investigates a prescribed-time trajectory tracking control strategy for USVs considering marine environmental interferences and unmodeled dynamics. Firstly, a fixed-time extended state observer is introduced to quickly and accurately observe
Bowen Sui +4 more
doaj +1 more source
Observers for invariant systems on Lie groups with biased input measurements and homogeneous outputs
, 2015 This paper provides a new observer design methodology for invariant systems whose state evolves on a Lie group with outputs in a collection of related homogeneous spaces and where the measurement of system input is corrupted by an unknown constant bias ...
Khosravian, Alireza +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Finite-Time Fault-Tolerant Control for Diesel Engine Air Path via Extended State Observer
IEEE Access, 2019 This paper investigates a finite-time observer-based fault-tolerant control scheme for the diesel engine air path, which suffers from loss-of-effectiveness and addictive actuator faults.
Wenhui Li +3 more
doaj +1 more source