Results 81 to 90 of about 9,609,480 (297)

Nonlinear Discrete Observer for Flexibility Compensation of Industrial Robots [PDF]

open access: yes, 2014
This paper demonstrates the solutions of digital observer implementation for industrial applications. A nonlinear high-gain discrete observer is proposed to compensate the tracking error due to the flexibility of robot manipulators. The proposed discrete
ABBA, Gabriel   +2 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

H ∞  sliding mode observer design for a class of nonlinear discrete time-delay systems: A delay-fractioning approach [PDF]

open access: yes, 2011
Copyright @ 2012 John Wiley & SonsIn this paper, the H ∞  sliding mode observer (SMO) design problem is investigated for a class of nonlinear discrete time-delay systems.
Zidong Wang   +7 more
core   +1 more source

Design of Reduced-Order Multiple Observers for Uncertain Systems with Unknown Inputs

open access: yesComplexity, 2018
The paper presents the design of a new reduced-order multiple observer for the estimation of the state associated with Takagi-Sugeno systems with unknown inputs, this being only the second reduced-order multiple observer ever designed.
Mihai Lungu
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Introducing Experience Goals into Packaging Design [PDF]

open access: yes, 2016
Consumer experiences are an increasingly important driving force for commerce, affecting also packaging design. Yet, experience design for packages is rarely studied.
Roto, Virpi   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Perspective: the gist of public tender for service design [PDF]

open access: yes, 2018
Governments around the world are increasingly formalising design as an innovative approach to renew public services. In this development, the capabilities of external service design consultancies often play an important part, which calls for new insights
Person, Oscar   +3 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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