Results 131 to 140 of about 516,287 (323)

Intra-Tumour Heterogeneity Is One of the Main Sources of Inter-Observer Variation in Scoring Stromal Tumour Infiltrating Lymphocytes in Triple Negative Breast Cancer. [PDF]

Cancers (Basel), 2021
Kilmartin D, O'Loughlin M, Andreu X, Bagó-Horváth Z, Bianchi S, Chmielik E, Cserni G, Figueiredo P, Floris G, Foschini MP, Kovács A, Heikkilä P, Kulka J, Laenkholm AV, Liepniece-Karele I, Marchiò C, Provenzano E, Regitnig P, Reiner A, Ryška A, Sapino A, Specht Stovgaard E, Quinn C, Zolota V, Webber M, Roshan D, Glynn SA, Callagy G.   +27 more
europepmc   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Reliability of the interpretation of coronary angiography by the simple visual method

Arquivos Brasileiros de Cardiologia, 2000
OBJECTIVE: Evaluation of inter and intraobserver reproducibility of by the visual method interpretation of cineangiogram in a clinically based context. METHODS: Five interventional cardiologists analyzed 11 segments of 8 coronary cineangiograms at a two ...
Guimarães Jorge Augusto Nunes, Victor Edgar Guimarães, Leite Maria do Rosário de Britto, Gomes José Maria Pereira, Victor Filho Edgar, Reyes Liveras Jesus   +5 more
doaj  

Inter-Observer Variation in Cardio-Pulmonary Resuscitation Scoring Systems [PDF]

, 1997
Desiree Henshaw, Mark Holland, Kevin Stewart, Mandy Gill   +3 more
openalex   +1 more source

Epidemiology for the uninitiated. Observer variation. [PDF]

BMJ, 1978
D J Barker, G Rose
openaire   +2 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Artificial intelligence in foot and ankle pathology: Can large language models replace us?

Journal of the Foot & Ankle
Objective: Determine if large language models (LLMs) provide better or similar information compared to an expert trained in foot and ankle pathology in various aspects of daily practice (definition and treatment of pathology, general questions). Methods:
Florencio Pablo Segura, Facundo Manuel Segura, Julieta Porta, Natalia Heredia, Ignacio Masquijo, Federico Anain, Leandro Casola, Agustina Trevisson, Virginia Cafruni, Maria Paz Lucero Zudaire, Ignacio Toledo, Florencio Vicente Segura   +11 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Observer variation in the diagnosis of superficial oesophageal adenocarcinoma: another spanner in the works? [PDF]

, 2002
Derek Alderson
openalex   +1 more source