Results 211 to 220 of about 980,903 (318)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Does a multimodal educational intervention involving pre-intern 'hand hygiene covert observers' improve hand hygiene compliance among medical interns? [PDF]

Antimicrob Resist Infect Control
Wong SC, Chiu EK, Chiu KH, Chau PH, Chau BY, Ng WY, Kwok MO, Yuen KY, Cheng VC.   +8 more
europepmc   +1 more source

Magnetic resonance image registration in multiple sclerosis: Comparison with repositioning error and observer‐based variability [PDF]

, 2002
I Leng Tan, Ronald A. van Schijndel, Marianne A.A. van Walderveen, M. Quist, Reinhard Bos, Petra J. W. Pouwels, Pol Desmedt, Herman J. Adèr, Frederik Barkhof   +8 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

LoQANT: An ImageJ Plugin for Quantifying Nuclear Staining in Immunohistochemistry and Immunofluorescence. [PDF]

Int J Mol Sci
Cizkova K.
europepmc   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Simultaneous State and Parameter Estimation Methods Based on Kalman Filters and Luenberger Observers: A Tutorial & Review. [PDF]

Sensors (Basel)
Chebbi A, Franchek MA, Grigoriadis K.
europepmc   +1 more source

Football Observers' Perceptions of Women's Football in Aceh

Tuti Sarwita, Nurzatul Shima, Zulheri Is, Didi Yudha Pranata, Zikrur Rahmat, Irfandi Irfandi, Munzir Munzir, Septi Hariansyah, Irwandi Irwandi   +8 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Features of interest from a multi-season satellite survey of baleen whales on the West Antarctic Peninsula. [PDF]

Sci Data
Bamford CCG, Cubaynes H, Kelly N, Clarke PJ, Longden E, Weyn M, Perry G, Snead H, Fouda L, Macfarlane G, Jackson JA.   +10 more
europepmc   +1 more source