Results 221 to 230 of about 909,800 (267)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Eye movements during free viewing to maximize scene understanding. [PDF]

Nat Commun
Murlidaran S, Eckstein MP.
europepmc   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Stimulus Center Bias Persists Irrespective of Its Position on the Display. [PDF]

J Eye Mov Res
Mairon R, Ben-Shahar O.
europepmc   +1 more source

Impact of international observerships on Ukrainian healthcare professionals during the war: a cross-sectional survey study. [PDF]

BMJ Open
Kovalchuk N, Zinchuk A, Beznosenko A, Semikov R, Poylin V, Vash-Margita A, Mims M, Davis D, Uboha N, Suchowerska N, Iakovenko V, Hart J, Poznansky M, Kacharian A, Kizub D, Melnitchouk S, Melnitchouk N.   +16 more
europepmc   +1 more source

Perceived Transparency from Dynamic Luminance Modulation in Uniform Center-Surround Displays. [PDF]

Vision (Basel)
Kim S, Kim SH.
europepmc   +1 more source

Measuring empathy in OSCEs: A comparison of student, standardized patient, and observer rating tools. [PDF]

PEC Innov
Hepner A, Cerutti B, Lüchinger R, Junod Perron N.   +3 more
europepmc   +1 more source

An Eye-Tracking Study of Pain Perception Toward Faces with Visible Differences. [PDF]

Behav Sci (Basel)
Rasset P, Séry L, Granjon M, Bogart K.
europepmc   +1 more source

Radiological Assessment of Inter- and Intra-observer Reliability in Hip Migration Measurements in Children With Cerebral Palsy at a Tertiary Referral Center. [PDF]

Cureus
Sajeev J, Kurian B, Lal JV, George A, Joseph J.   +4 more
europepmc   +1 more source