Results 91 to 100 of about 4,753,165 (342)

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

Cost-effectiveness of screening for colorectal cancer with once-only flexible sigmoidoscopy and faecal occult blood test [PDF]

On the basis of a randomized controlled trial we estimate the cost per life-year gained for six different strategies for colorectal cancer screening. Individuals in the age group 50 to 64 years were randomly selected for either flexible sigmoidoscopy or ...
Aas, Eline
core  

Review of economic evidence in the prevention and early detection of colorectal cancer. [PDF]

, 2013
This paper aims to systematically review the cost-effectiveness evidence, and to provide a critical appraisal of the methods used in the model-based economic evaluation of CRC screening and subsequent surveillance.
Kim E Jeong, Cairns, John A, Jeong, Kim E., John A Cairns, Jeong, Kim E, Cairns, John A.   +5 more
core   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Conceptualising quality early childhood education: Learning from young children in Brazil and South Africa through creative and play‐based methods

British Educational Research Journal, EarlyView., 2023
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright, Irene Rizzini, Malibongwe Gwele, Lynn McNair, Cristina Laclette Porto, Marsha Orgill, E. Kay M. Tisdall, Malcolm Bush, Linda Biersteker   +8 more
wiley   +1 more source

Comment on “Fecal occult blood versus DNA testing: indirect comparison in a colorectal cancer screening population” [PDF]

, 2017
David A Ahlquist Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USAChallenges to medical innovation are welcome and essential elements in the dialectic toward practice optimization but must be based on scientifically sound ...
Ahlquist DA
core  

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

The impact of supplementary narrative-based information on colorectal cancer screening beliefs and intention [PDF]

, 2015
Background: The potential benefits of colorectal cancer screening are limited by low uptake. This study tested whether providing narrative accounts of the colorectal cancer (CRC) screening experience positively affected beliefs about CRC screening and ...
McGregor, Lesley M, von Wagner, Christian, Raine, Rosalind, Wing Chee Yuen, von Wagner, C, Raine, R, Christian von Wagner, Robb, Kathryn A, Vart, Gemma, McGregor, LM, Kathryn A Robb, Robb, KA, Robb, Kathryn A., Jane Wardle, Wardle, Jane, Lesley M McGregor, McGregor, Lesley M., Rosalind Raine, Yuen, WC, Yuen, Wing Chee, Gemma Vart, Wardle, J, Vart, G   +22 more
core   +1 more source

Comparison of Changes in Biomarkers With Changes in Endoscopic Scores in Patients With Ulcerative Colitis: A Single‐Center, Retrospective, Observational Study

JGH Open
Aim Fecal occult blood concentration, fecal calprotectin (FC) level, serum C‐reactive protein (CRP) level, and erythrocyte sedimentation rate (ESR) are valuable biomarkers for ulcerative colitis (UC).
Yosuke Yamada, Natsuki Ishida, Tomohiro Takebe, Kenichi Takahashi, Yusuke Asai, Mihoko Yamade, Moriya Iwaizumi, Yasushi Hamaya, Takanori Yamada, Satoshi Osawa, Ken Sugimoto   +10 more
doaj   +1 more source

Validity of Fecal Occult Blood Test in the National Cancer Screening Program, Korea

PLoS ONE, 2013
Aim The aims of the current study were to assess the validity of the fecal occult blood test (FOBT) in an organized screening setting in Korea and to determine factors associated with FOBT validity, such as screening round, age group, and anatomical ...
A. Shin, K. Choi, J. Jun, D. K. Noh, Mina Suh, K. Jung, Byung Chang Kim, J. Oh, E. Park   +8 more
semanticscholar   +1 more source