Results 51 to 60 of about 543,570 (317)

Lysosomal iron accumulation and subsequent lysosomes-mitochondria iron transmission mediate PFOS-induced hepatocyte ferroptosis

Ecotoxicology and Environmental Safety
Perfluorooctane sulfonate (PFOS) is known as a persistent organic pollutant. A significant correlation between PFOS and liver ferroptosis has been unveiled, but the precise mechanism needs to be elucidated. In prior research, we found that PFOS treatment
Jixun Li, Ruzhen Feng, Wei Yang, Peiyao Liang, Tianming Qiu, Jingyuan Zhang, Xiance Sun, Qiujuan Li, Guang Yang, Xiaofeng Yao   +9 more
doaj   +1 more source

Changes in Muscle Activation During and After a Shoulder-Fatiguing Task: A Comparison of Elite Female Swimmers and Water Polo Players

Frontiers in Sports and Active Living, 2022
This study compared female athletes with different aquatic sports expertise in their neuromuscular activation before, during, and after a shoulder internal rotation fatigue protocol.
Savannah King, Lily Dong, Michelle Caron, Julie N. Côté   +3 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Djadjiling Rockshelter: 35,000 ¹⁴C Years of Aboriginal Occupation in the Pilbara, Western Australia [PDF]

, 2010
The Pleistocene settlement of the arid zone is a prominent research theme in Australian archaeology (Hiscock 2008:45- 62; Hiscock and Wallis 2004; Marwick 2002a, 2002b; O’Connor et al. 1998; Smith 1987, 2005; Thorley 1998; Veth 1993, 1995, 2005).
Cropper, Dawn, Petchey, F., Cropper, D., Cropper, Dawn N., Law, W., Law, W. Boone, Petchey, Fiona   +6 more
core   +1 more source

Occupation-wise distribution of mood status of HCPs based on their gender.

, 2021
Occupation-wise distribution of mood status of HCPs based on their gender.
Sanjiv Rao (11495656), Prem Kumar B. N. (11495671), Sridhar K. (11495674), Manohar K. N. (11495647), Vivek Verma (575280), Sekhar Y. (11495659), Vijay Kumar K. (11495662), Amalselvam A. (11495665), Pradeep Kumar S. (11495677), Hemkumar T. R. (11495668), C. R. Satish Kumar (11495653), Neha Parashar (11495650), Judith (11495686), Shivam (11495683), Sangeeta K. (11495680), Chetan Kumar (13770)   +15 more
core   +1 more source

The VDAC1 oligomerization regulated by ATP5B leads to the NLRP3 inflammasome activation in the liver cells under PFOS exposure

Ecotoxicology and Environmental Safety
As a persistent organic pollutant, perfluorooctane sulfonate (PFOS) has a serious detrimental impact on human health. It has been suggested that PFOS is associated with liver inflammation. However, the underlying mechanisms are still unclear.
Yu Ma, Wei Yang, Peiyao Liang, Ruzhen Feng, Tianming Qiu, Jingyuan Zhang, Xiance Sun, Qiujuan Li, Guang Yang, Xiaofeng Yao   +9 more
doaj   +1 more source

Work participation of patients with musculoskeletal disorders: is this addressed in physical therapy practice?

Journal of Occupational Medicine and Toxicology, 2017
Background Musculoskeletal disorders are the main complaints for visiting a physical therapist (PT) in primary health care; they have a negative effect on an individual’s quality of life and result in a major cost to society.
Wiebke Oswald, Nathan Hutting, Josephine A. Engels, J. Bart Staal, Maria W. G. Nijhuis-van der Sanden, Yvonne F. Heerkens   +5 more
doaj   +1 more source

The HOME-Health (HOusing, environMEnt, and Health) Study; Description of a Danish natural experiment, designed as a longitudinal study with repeated measurements, providing internal- and external validity of the study

Environmental Health Insights, 2023
Background: The ambient and indoor environment are pivotal to our health. We spend most of our time indoors within our home, why our home is where we are most exposed to indoor pollutants and indoor air quality (IAQ).
Charlotte Gabel, Grethe Elholm, Mia Kruse Rasmussen, Thea Hauge Broholt, Stina Rask Jensen, Steffen Petersen, Torben Sigsgaard   +6 more
doaj   +1 more source

Phage Therapy for Multi-Drug Resistant Respiratory Tract Infections

Viruses, 2021
The emergence of multi-drug resistant (MDR) bacteria is recognised today as one of the greatest challenges to public health. As traditional antimicrobials are becoming ineffective and research into new antibiotics is diminishing, a number of alternative ...
Joshua J. Iszatt, Alexander N. Larcombe, Hak-Kim Chan, Stephen M. Stick, Luke W. Garratt, Anthony Kicic   +5 more
doaj   +1 more source