Results 151 to 160 of about 231,858 (266)

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo   +13 more
wiley   +1 more source

Domain-specific physical activity levels and risk of dementia: a systematic review and meta-analysis. [PDF]

open access: yesLancet Public Health
Feter N   +18 more
europepmc   +1 more source

Toward a Behavioral Reserve Model in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Behavioral impairment is common in amyotrophic lateral sclerosis (ALS) and strongly affects autonomy, caregiver burden, and outcomes, yet predictors of vulnerability remain unclear. We investigated whether premorbid regulatory traits and socio‐educational exposures are associated with behavioral phenotypes in ALS within a behavioral reserve ...
Francesca Palumbo   +14 more
wiley   +1 more source

Differential Associations of Occupational and Total Physical Activity with Sleep Quality Among Adults in the United Arab Emirates: A Cross-Sectional Study. [PDF]

open access: yesInt J Environ Res Public Health
Aljawarneh Y   +10 more
europepmc   +1 more source

Genetic Resilience and Resistance in Alzheimer's Disease Diagnosis and Pathology

open access: yesAnnals of Neurology, EarlyView.
Objective Some individuals avoid Alzheimer's disease (AD) pathology as they age, or retain cognition despite substantial pathology, suggesting mechanisms of resistance or resilience to neurodegeneration. Educational attainment (EA) is associated with reduced risk of cognitive decline, although the underlying mechanisms remain unclear.
Ganna Leonenko   +8 more
wiley   +1 more source

Factors Associated with Smoking Status and Self-Reported Physical Activity Among Spanish Nursing Professionals: A Cross-Sectional Study. [PDF]

open access: yesNurs Rep
Cuervo-Menéndez JM   +5 more
europepmc   +1 more source

Local variation in age‐related cortical expansion within and between cross‐sections of distal human long bones

open access: yesThe Anatomical Record, EarlyView.
Abstract Cortical bone expansion is an age‐related process where, through endosteal resorption and periosteal apposition, cross‐sectional diameter increases while cortical thickness decreases in long bone diaphyses. Local variation has been observed in this process between cross‐sectional locations, but few studies have examined directional variation ...
Gregory J. Wehrman   +4 more
wiley   +1 more source

Mapping the distribution of Meissner corpuscles throughout the human hand: Sex‐ and age‐dependent variations

open access: yesThe Anatomical Record, EarlyView.
Abstract Meissner corpuscles are rapidly adapting mechanoreceptors involved in tactile discrimination in human glabrous hand skin. Detailed information on their regional distribution and variation across age, sex, and hand side remains limited. This study mapped Meissner corpuscles in 17 phalangeal and palmar regions from 46 individuals (27 male and 19
Irene Amigo   +7 more
wiley   +1 more source

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