Results 41 to 50 of about 12,043,419 (301)

Device-measured physical activity, sedentary behaviour and cardiometabolic health and fitness across occupational groups: a systematic review and meta-analysis

International Journal of Behavioral Nutrition and Physical Activity, 2019
BackgroundWith approximately 8 hours of one’s waking day spent at work, occupational tasks and environments are important influencers on an individual’s physical activity (PA) and sedentary behaviours.
S. Prince, Cara G. Elliott, Kyle Scott, S. Visintini, J. Reed   +4 more
semanticscholar   +1 more source

Factors affecting the maintenance of occupational activity over a 2–3-year period after total hip replacement

Medycyna Pracy, 2018
Background The purpose of this paper was to assess the occupational activity in patients after hip replacement over a 2–3-year post operational period and to analyze the effect of selected factors (age, gender, body mass index (BMI), functional state ...
Teresa Pop, Agnieszka Bejer, Joanna Baran, Daniel Szymczyk   +3 more
doaj   +1 more source

Assessing Veterans’ Lived Experiences After Exposure to an Autonomous Shuttle

Future Transportation
Transportation is often cited as a significant barrier to healthcare access by Veterans, particularly those from minority groups, who have disabilities, or live in rural areas. Autonomous shuttles (AS) offer a potential solution, yet limited research has
Isabelle Wandenkolk, Sherrilene Classen, Nichole E. Stetten, Seung Woo Hwangbo, Kelsea LeBeau   +4 more
doaj   +1 more source

Effect of occupational activity on ambulatory blood pressure profile in university teachers

International Journal of Occupational and Environment Safety, 2018
Hypertension (HBP), a key risk factor for cardiovascular diseases, is strongly associated with behavioral and environmental aspects of living. Professional activities, amongst others that take place throughout the day, are responsible for important blood
J. Pereira, H. Simões
doaj   +1 more source

Barriers to cross-disciplinary knowledge flow: The case of medical education research

Perspectives on Medical Education, 2021
Introduction The medical education research field operates at the crossroads of two distinct academic worlds: higher education and medicine. As such, this field provides a unique opportunity to explore new forms of cross-disciplinary knowledge exchange ...
Mathieu Albert, Paula Rowland, Farah Friesen, Suzanne Laberge   +3 more
doaj   +1 more source

Occupational physical activities and osteoarthritis of the knee [PDF]

Arthritis & Rheumatism, 2000
To assess the risk of knee osteoarthritis (OA) associated with kneeling, squatting, and other occupational activities.We compared 518 patients who were listed for surgical treatment of knee OA and an equal number of control subjects from the same communities who were matched for sex and age.
Coggon, D., Croft, P., Kellingray, S., Barrett, D.S., McLaren, M., Cooper, C.   +5 more
openaire   +3 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Health and quality of life vs. occupational activity

Medycyna Pracy, 2016
The level of quality of life and health status of the population largely depends on the determinants related to occupational activity. The results of reviewed bibliography indicate a significant and growing importance of employment conditions on the ...
Małgorzata Kowalska, Szymon Szemik
doaj   +1 more source

Body mass index, occupational activity, and leisure-time physical activity: an exploration of risk factors and modifiers for knee osteoarthritis in the 1946 British birth cohort

BMC Musculoskeletal Disorders, 2013
BackgroundKnee osteoarthritis (kOA) risk is increased by obesity and physical activities (PA) which mechanically stress the joint. We examined the associations of midlife kOA with body mass index (BMI) and activity exposure across adult life and their ...
K. Martin, D. Kuh, T. Harris, J. Guralnik, D. Coggon, A. Wills   +5 more
semanticscholar   +1 more source

Stabilization of Glucocerebrosidase by Active Site Occupancy [PDF]

ACS Chemical Biology, 2017
Glucocerebrosidase (GBA) is a lysosomal β-glucosidase that degrades glucosylceramide. Its deficiency results in Gaucher disease (GD). We examined the effects of active site occupancy of GBA on its structural stability. For this, we made use of cyclophellitol-derived activity-based probes (ABPs) that bind irreversibly to the catalytic nucleophile (E340),
Ben Bdira, F., Kallemeijn, W.W., Oussoren, S.V., Scheij, S., Bleijlevens, B., Florea, B.I., Roomen, C.P.A.A. van, Ottenhoff, R., Kooten, M.J.F.M. van, Walvoort, M.T.C., Witte, M.D., Boot, R.G., Ubbink, M., Overkleeft, H.S., Aerts, J.M.F.G.   +14 more
openaire   +6 more sources