Results 31 to 40 of about 173,424,084 (238)

The prevalence and profiles of adverse childhood experiences and their associations with adult mental health outcomes in China: a cross-sectional studyResearch in context

open access: yesThe Lancet Regional Health. Western Pacific
Summary: Background: Adverse childhood experiences (ACEs) are common and associated with mental disorders. However, the prevalence and co-occurrence of ACEs and their association with mental health outcomes among Chinese adults have not been well ...
Peilin Xu   +17 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Influence of Interface Modulation on Tribological Performance and Friction Mechanism of CQDs-Enhanced DLC/PAO Composite Systems [PDF]

open access: yesCailiao Baohu
With the rapid development of advanced manufacturing industries such as construction machinery,aerospace,and marine equipment,mechanical moving components suffer severe friction and wear.
XU Fengqin, LU Shiqi, DING Jiaqing, WEI Xubing, LIU Dongtao, LUO Meng, MA Bin, ZHANG Tiancai, LI Xiaowei
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Reinforcement requirements for secondary composite beams incorporating trapezoidal decking

open access: yes, 2006
Secondary composite beams incorporating trapezoidal profiled steel sheeting laid transverse to the longitudinal axis of the steel beam can exhibit unwanted brittle failure modes with low stud strength and poor ductility.
Ernst, Stefan   +3 more
core   +1 more source

Without doing factorization, a new method to find two large prime numbers of any composite numbers.

open access: yes, 2020
- This research is all about the biggest question... is it possible that without using factorization method can we find two prime numbers factors of any given product (composite number)? Answer is yes....
olvine
core   +1 more source

Splitting dynamics of quantized composite vortices in holographic miscible binary superfluids

open access: yesJournal of High Energy Physics
The stability properties and splitting dynamics of multiply quantized vortices are the subject of interest in both theoretical and experimental investigations. Going beyond the regime of validity of Gross-Pitaevskii equation (GPE), we study the composite
Yu-Ping An, Li Li
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Design of composite columns : steel, concrete or composite approach?

open access: yes, 2011
Composite columns are a combination of two traditional structural forms: structural steel and structural concrete. As composite columns were generally developed after steel columns and reinforced concrete columns, their design approach could have been ...
Russell Q. Bridge   +1 more
core   +1 more source

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