Results 131 to 140 of about 919 (164)

Pharmacological adjuvants for diabetic vitrectomy surgery. [PDF]

World J Methodol
Venkatesh R, Jayadev C, Prabhu V, Gandhi P, Kathare R, Yadav NK, Choudhary A, Chhablani J.   +7 more
europepmc   +1 more source

Integrating multi-tissue expression and splicing data to prioritise anatomical subsite- and sex-specific colorectal cancer susceptibility genes with therapeutic potential

Hazelwood E, Canson DM, Wang X, Kho PF, Legge D, Constantinescu A, Lee MA, Bishop DT, Chan AT, Gruber SB, Hampe J, Marchand LL, Woods MO, Pai RK, Schmit SL, Figueiredo JC, Zheng W, Huyghe JR, Murphy N, Gunter MJ, Richardson TG, Whitehall VLJ, Vincent EE, Glubb DM, O’Mara TA.   +24 more
europepmc   +1 more source

Multi-tissue expression and splicing data prioritise anatomical subsite- and sex-specific colorectal cancer susceptibility genes. [PDF]

Nat Commun
Hazelwood E, Canson DM, Deslandes B, Wang X, Kho PF, Legge D, Constantinescu AE, Lee MA, Bishop DT, Chan AT, Gruber SB, Hampe J, Le Marchand L, Woods MO, Pai RK, Schmit SL, Figueiredo JC, Zheng W, Huyghe JR, Murphy N, Gunter MJ, Richardson TG, Whitehall VLJ, Vincent EE, Glubb DM, O'Mara TA.   +25 more
europepmc   +1 more source

Enzymatic Vitreolysis With Ocriplasmin for Vitreomacular Traction and Macular Holes [PDF]

New England Journal of Medicine, 2012
Background: vitreomacular adhesion can lead to pathologic traction and macular hole. The standard treatment for severe, symptomatic vitreomacular adhesion is vitrectomy. Ocriplasmin is a recombinant protease with activity against fibronectin and laminin,
Peter Stalmans, Julia Haller, Anselm Kampik   +2 more
exaly   +5 more sources

Effectiveness of Ocriplasmin in Real-World Settings: A Systematic Literature Review, Meta-Analysis, and Comparison With Randomized Trials

Acta Ophthalmologica, 2021
Abstract Purpose Effectiveness of ocriplasmin for vitreomacular traction (VMT) varies depending on the presence of common ocular conditions and patient selection criteria. We carried out a systematic literature review and meta‐analysis of ocriplasmin studies conducted in real‐world settings (RWS) and compared outcomes with those from randomized ...
Arshad M Khanani, Koenraad Blot, Benedicte Lescrauwaet   +2 more
exaly   +2 more sources

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Ocriplasmin

Reactions Weekly, 2015
  +12 more sources

Results of the 2-Year Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole (OASIS) Randomized Trial

Ophthalmology, 2016
Purpose The Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole (OASIS) trial was designed to evaluate the long-term efficacy and safety profile of ocriplasmin for the treatment of symptomatic vitreomacular adhesion ...
Pravin U Dugel, Michael Tolentino
exaly   +2 more sources

Ocriplasmin

Reactions Weekly, 2016
  +9 more sources

From the Analysis of Pharmacologic Vitreolysis to the Comprehension of Ocriplasmin Safety

Expert Opinion on Drug Safety, 2016
Introduction: Pharmacologic vitreolysis is a strategy used to treat anomalous posterior vitreous detachment, by weakening vitreoretinal adhesion with an intravitreal drug.
Elena Gambicorti, Ciro Costagliola, Francesco Semeraro   +2 more
exaly   +2 more sources

Safety and Complications of Ocriplasmin

JAMA Ophthalmology, 2014
Our ability to examine the vitreoretinal interface has been greatly improved by the invention of spectral-domain optical coherence tomography (OCT). It has allowedearlier andmore accurate diagnosis of abnormalities of vitreomacular adhesion (VMA) that may contribute to vision loss and may benefit fromintervention.While subtle abnormalitiesofVMAmay be ...
openaire   +2 more sources