Results 191 to 200 of about 22,517 (214)
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Structure of octreotide, a somatostatin analogue
Acta Crystallographica Section D Biological Crystallography, 1995Octreotide, a synthetic somatostatin analogue, is an octapeptide with one disulfide bridge. Crystals of octreotide are orthorhombic, space group P2(1)2(1)2(1), a = 18.458 (5), b = 30.009 (7), c = 39.705 (27) A, with three molecules of octapeptide, one ordered oxalate dianion and 52 water molecules in the asymmetric unit.
Pohl, E.+7 more
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Graves' Dermopathy: Does Octreotide Scintigraphy Predict the Response to Octreotide Treatment?
Thyroid, 1996We report on three patients with severe Graves' dermopathy who were treated with octreotide despite a negative octreotide scintigraphy. One patient showed a complete recovery while two others had a partial response. In contrast to active Graves' ophthalmopathy, an octreotide scintigraphy appears not to be useful for pretreatment identification of ...
Wilmar M. Wiersinga+3 more
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Octreotide (Sandostatin, Sandoz)
Intensive and Critical Care Nursing, 1996Octreotide is a unique compound which 'switches off' inappropriate secretory activity in many conditions. Its clinical applications have been steadily increasing since its introduction in the UK just over 5 years ago.
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Octreotide Scintigraphy for the Detection of Paragangliomas
Otolaryngology–Head and Neck Surgery, 2000Paragangliomas are neuroendocrine tumors located primarily in the head and neck region, but they can also occur at other sites. Confirming the preoperative diagnosis and detecting synchronous tumors may be difficult in some patients. Octreotide is a somatostatin analog that, when coupled to a radioisotope, produces a scintigraphic image of tumors ...
Thomas J. Balkany+7 more
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Octreotide for the treatment of chylothorax in neonates
Cochrane Database of Systematic Reviews, 2007Routine care for chylothorax in neonate includes either conservative or surgical approaches. Octreotide, a somatostatin analogue, has been used for the management of patients with refractory chylothorax not responding to conservative management.To assess the efficacy and safety of octreotide in the treatment of chylothorax in neonates.We searched the ...
Prakeshkumar S Shah, Animitra Das
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Sandostatin (Octreotide Acetate)
Gastroenterology Nursing, 1992Sandostatin is an antineoplastic drug used to control diarrhea and improve hypokalema in patients with metastatic carcinoid tumors and vasoactive intestinal peptide-secreting tumors. Sandostatin has been used to treat life-threatening hypotension and acromegaly.
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Octreotide for treatment of postoperative chylothorax
The Journal of Pediatrics, 2001Two infants who developed chylothorax after surgery for congenital heart disease were treated successfully with subcutaneous octreotide. Apart from reducing chyle output, octreotide decreased the triglyceride content of the pleural fluid.
Cheung, YF, Leung, MP, Yip, MM
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Baillière's Clinical Gastroenterology, 1994
This chapter reviews the therapeutic use of octreotide in a variety of pancreatic disorders, including acute pancreatitis, in the prevention of postoperative and post-ERCP pancreatitis, in the control of postoperative pancreatic fistulae, and in chronic pancreatitis for the control of pain and of pseudocysts and ascites.
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This chapter reviews the therapeutic use of octreotide in a variety of pancreatic disorders, including acute pancreatitis, in the prevention of postoperative and post-ERCP pancreatitis, in the control of postoperative pancreatic fistulae, and in chronic pancreatitis for the control of pain and of pseudocysts and ascites.
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Treatment of pancreatic pseudocysts with octreotide
The Lancet, 1991Pancreatic pseudocysts are a common and painful complication of chronic pancreatitis. Seven patients (six male, one female; mean age 49.9 years) with chronic pancreatitis complicated by pseudocysts and persistent pain were treated with the pancreatic anti-secretory drug octreotide for 2 weeks.
Luigi Barbara, L Gullo
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Octreotide in the Treatment of Refractory Diarrhea
Digestion, 1999Refractory chronic diarrhea that does not respond to specific antimicrobial therapy or standard unspecific medication may present a challening and serious clinical problem. Octreotide is a candidate drug for the treatment of these patients as it inhibits gastrointestinal motility, pancreatic secretion and inhibits intestinal absorption. Only few mostly
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