Results 81 to 90 of about 49,463 (304)

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Predictive information and error processing : the role of medial-frontal cortex during motor control

, 2007
We have recently provided evidence that an error-related negativity (ERN), an ERP component generated within medial-frontal cortex, is elicited by errors made during the performance of a continuous tracking task (O.E. Krigolson & C.B. Holroyd, 2006).
Holroyd, Clay, Krigolson, Olav E.
core   +1 more source

Characterization of Vitamin D Production by Human Ocular Barrier Cells [PDF]

Investigative Opthalmology & Visual Science, 2014
Vitamin D3 is a secosteroid mainly synthesized from the conversion of the skin precursor 7-dehydrocholesterol (7DHC) to vitamin D3 by ultraviolet (UV) B sunlight. Extrarenal synthesis of vitamin D3 has been reported in many tissues and cells, including barrier sites. This study characterizes the expression of components of vitamin D3 signaling in human
Jawaher A, Alsalem, Deepali, Patel, Radhika, Susarla, Miguel, Coca-Prados, Rosemary, Bland, Elizabeth A, Walker, Saaeha, Rauz, Graham R, Wallace   +7 more
openaire   +2 more sources

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Long‐Acting Ocular Injectables: Are We Looking In The Right Direction?

Advanced Science
The complex anatomy and physiological barriers of the eye make delivering ocular therapeutics challenging. Generally, effective drug delivery to the eye is hindered by rapid clearance and limited drug bioavailability.
Mickael Dang, Molly S. Shoichet
doaj   +1 more source

Ocular morbidity and utilisation of protective eyewear among carpenters in Mushin local government, Lagos, Nigeria

Nigerian Postgraduate Medical Journal, 2019
Context: Proper use of protective eyewear (PEW) is important in the prevention of occupational eye injury. Aim: The aim of this study was to determine the ocular morbidity and utilisation of PEW among carpenters in Mushin Local Government, Lagos, with a ...
Onyinyechukwu Mary-Angela Onyekwelu, Olufisayo Temitayo Aribaba, Kareem Olatunbosun Musa, Oluwatobi Olalekan Idowu, Monsurah Olabimpe Salami, Yvonne Nwamaka Odiaka   +5 more
doaj   +1 more source

Diclofenac sodium ion exchange resin complex loaded melt cast films for sustained release ocular delivery

, 2017
The goal of the present study is to develop polymeric matrix films loaded with a combination of free diclofenac sodium (DFSfree) and DFS:Ion exchange resin complexes (DFS:IR) for immediate and sustained release profiles, respectively.
Adelli, Goutham R., Balguri, Sai Prachetan, Bhagav, Prakash, Majumdar, Soumyajit, Raman, Vijayasankar   +4 more
core   +2 more sources

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Current trends among pediatric ophthalmologists to decrease myopia progression—an international perspective [PDF]

, 2018
Purpose To explore what the current worldwide preferred practice patterns of pediatric ophthalmologists are to decrease myopia progression among their patients.
Farzavandi, Sonal K., Gomez-de-Liaño, Rosario, Mezer, Eedy, Sprunger, Derek T., Wygnanski-Jaffe, Tamara, Zloto, Ofira   +5 more
core   +1 more source

Ocular Drug Delivery System: Barrier for Drug Permeation, Method to Overcome Barrier

, 2022
The physiological and anatomical barriers are major obstacles in the field of ocular drug delivery systems. The barriers involve nasolacrimal drainage, blinking, cornea, sclera, and blood-aqueous barriers whereas dynamic barriers involve conjunctival blood flow, lymphatic clearance and tear drainage.
Prakriti, Diwan,, Rajendra, Jangde,, Sulekha, Khunte,, Harish, Bhardwaj,, K., Suresh, Preeti   +4 more
openaire   +2 more sources