Results 61 to 70 of about 1,164,846 (257)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Long-term effect of latanoprost/timolol fixed combination in patients with glaucoma or ocular hypertension: a prospective, observational, noninterventional study [PDF]

, 2010
Background: Prospective, observational studies that enroll large numbers of patients with few exclusion criteria may better reflect actual ongoing clinical experience than randomized clinical trials.
Guzy, Claudia, Miller Paul J, Oliver Schwenn, Schwenn, Oliver, Heckmann Barbara, Paul J Miller, Schwenn Oliver, Barbara Heckmann, Claudia Guzy, Miller, Paul J., Heckmann, Barbara, Guzy Claudia   +11 more
core   +2 more sources

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Systemic and Bilateral Severe Ocular Toxoplasmosis Resembling Autoimmune Phenomena: A Case Report

Purpose: To present an atypical case of severe bilateral ocular toxoplasmosis with systemic involvement that initially mimicked an autoimmune etiology, posing challenges to its diagnosis and treatment.
Muñoz-Ortiz J., Romero-Santos S., Mejía-Salgado G., de-la-Torre A., Cifuentes-González C., Parra-Tanoux D.   +5 more
core   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Topical Ocular Drug Delivery: The Impact of Permeation Enhancers

Pharmaceutics
Topical ophthalmic drug delivery targeting the posterior segment of the eye has become a key area of interest due to its non-invasive nature, safety, ease of application, patient compliance, and cost-effectiveness.
Gonçalo Santos, Esmeralda Delgado, Beatriz Silva, Berta São Braz, Lídia Gonçalves   +4 more
doaj   +1 more source

Determination of Ocular Blood Flows with the Microsphere Method

, 2012
Adequate blood supply to the eye is an important prerequisite for normal visual function. Over the past 40 years our knowledge of ocular blood flow regulation has improved significantly.
Siv F. E. Nilsson, Albert Alm, Nilsson, Siv,, Alm, Albert,   +3 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Impacts of Nanomedicines in Ocular Pharmacotherapy

BioImpacts, 2011
Introduction: The integrity of the cells/tissues in anterior and/or posterior segments of the eye plays a crucial role in biofunctions of the vision.
Jaleh Barar, Ailar Nakhlband
doaj   +1 more source

A review of novel nanoformulations for treatment of dry eye disease and ocular surface inflammation [PDF]

Nanomedicine Journal
Dry eye disease (DED) is a multifactorial condition frequently encountered in ocular disorders. DED not only causes ocular discomfort but also leads to damage to the cornea and conjunctiva.
Alireza Nouralishahi, Navid Fazlinejad, Mohamad Saeid Hoseinzade Firozabadi, Saman Mohammadzadehsaliani, Rand Otbah Farqad, Haider Radhi Saud, Hadis Kheradjoo   +6 more
doaj   +1 more source