Results 41 to 50 of about 1,164,846 (257)

Preparação e caracterização de nanopartículas contendo metotrexato: avaliação da estabilidade e viabilidade do tecido corneal após administração tópica ocular [PDF]

open access: yes, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em FarmáciaA instilação tópica ocular é a forma mais comum de tratamento de patologias oftálmicas, sendo a córnea a principal barreira
Sartori, Tatiane
core  

Ocular dirofilariasis: a clinicopathologic case series and literature review

open access: yes, 2023
Purpose Ocular dirofilariasis is an uncommon zoonotic infection that is usually associated with a carnivore host. In this case series and literature review we investigate the clinical presentation, management, and histopathology of ocular dirofilariasis.
Clauss, Kevin D.   +10 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Calling all Writers! [PDF]

open access: yes, 2020
You are viewing a news article about Good Systems from 2020.Office of the VP for ...
UT Austin, Bridging Barriers
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

open access: yesAdvanced Science
Pathological retinal and choroidal neovascularization is a hallmark of several blinding diseases, including diabetic retinopathy and age‐related macular degeneration.
Chong Chen   +12 more
doaj   +1 more source

Ophthalmic Drug Delivery Systems : An Update

open access: yesDelhi Journal of Ophthalmology, 2011
Drugs developed and approved for systemic disease are reinvestigated for ocular disease. However, developing new drugs with good intraocular penetration by considering the anatomical and physiological constraints exerted by the various barriers of eye is
Nihar Ranjan Biswas
doaj   +1 more source

Diagnóstico de tuberculose ocular

open access: yes, 2016
A tuberculose ocular continua sendo um diagnóstico clínico presuntivo, pois os testes padrão-ouro para diagnosticar a tuberculose ocular geralmente não são úteis: as culturas de Mycobacterium tuberculosis requerem semanas para serem processadas em meio ...
Marcus Ang   +7 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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