Results 101 to 110 of about 70,301 (300)

Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]

, 2019
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core   +1 more source

Real‐world Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, Accepted Article.
Objectives Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), yet the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to: 1) identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel MPH, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Composite bi-layered erodible films for potential ocular drug delivery [PDF]

, 2016
Bi-layered hydroxypropylmethylcellulose and Eudragit based films were formulated as potential ocular drug delivery systems using chloramphenicol as a model antibiotic.
A.M. Popescu, Aburahma, Amar, Andrews, Anshu, Aulton, Boateng, Boateng, Boateng, Carvalho, Cristescu, Fraunfelder, Gaudana, Ghosal, Gulsen, Gupta, Harris, Hehl, Hermans, J.S. Boateng, Jethava, Jung, Kesarwani, Kianfar, Kumar, Lai, Lam, Ludwig, Momoh, Morales, Nisha, Pahuja, Patel, Pflugfelder, Rajasekaran, Rathod, Tangri, Titcomb   +37 more
core   +1 more source

Perceived Impacts and Predictors of Cannabis Products used by Rheumatology Patients in Alberta: A Multivariable Analysis of Cross‐sectional Survey Data

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among rheumatology patients, and their associations with patient factors, patient reported perceived side effects and positive impacts. Methods An online survey (delivered from March to November 2022) was distributed by Alberta Health Services to ...
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Ophthalmology: Navigating ocular barriers with advanced nanocarriers

German Journal of Pharmaceuticals and Biomaterials
The unique anatomy and physiology of the eye present significant challenges for effective drug delivery, necessitating innovative approaches to manage ocular diseases.
Sanaul Mustafa
doaj   +1 more source

HYALURONIC ACID DERIVATIVE MICELLES AS OCULAR PLATFORMS TO DRUG RELEASE AND CORNEAL PERMEATION [PDF]

, 2016
In traditional ocular formulations, only small amount of the administered drug penetrates the cornea to reach the intraocular tissue. One approach to improve the drug ocular bioavailability was to develop colloidal drug delivery systems.
Bongiovì, Flavia, Di Prima, Giulia, GIAMMONA, Gaetano, LICCIARDI, Mariano, PALUMBO, Fabio Salvatore, PITARRESI, Giovanna   +5 more
core  

Comparison between “early” or “late” intravitreal injection of dexamethasone implant in branch (BRVO) or central (CRVO) retinal vein occlusion: six months follow-up [PDF]

, 2017
AIM: The aim of this study was to compare early and late injections of intravitreal dexamethasone implant in patients affected by central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) with a six-months follow-up.
AUTOLITANO, MONICA, BASILI, Stefania, LA TORRE, Giuseppe, LENZI, TOMMASO, PACELLA, Elena, PACELLA, FERNANDA, Pascarella, Antonella   +6 more
core   +1 more source

Packaging of Macroscopic Material Payloads: Needs, Challenges, Concepts, and Future Directions

Advanced Engineering Materials, EarlyView.
This review introduces a unified framework that decomposes any macroscopic packaging system into the payload, packaging material, and packaging strategy and combines them into a conceptual packaging equation: packaging strategy = payload + packaging material.
Venkata S. R. Jampani, Manos Anyfantakis
wiley   +1 more source

Light-responsive polymeric nanoparticles for retinal drug delivery: design cues, challenges and future perspectives

Heliyon
A multitude of sight-threatening retinal diseases, affecting hundreds of millions around the globe, lack effective pharmacological treatments due to ocular barriers and common drug delivery limitations.
Lorenzo Guidi, Maria Grazia Cascone, Elisabetta Rosellini   +2 more
doaj   +1 more source

The preparation of HEMA-MPC films for ocular drug delivery [PDF]

, 2017
There is a need to prolong drug residence time using a biocompatible formulation in the subconjunctival space after surgery to treat glaucoma. Drug releasing discs were prepared with 2-(hydroxyethyl)methacrylate (HEMA) and 2-methacryloyl-oxyethyl ...
Bettin, P. & Di Matteo, F.,, Brubaker, R.F.,, Chen, S. et al.,, Chong, R.S. et al.,, Cui, L. et al.,, Dhingra, S. & Khaw, P.,, Du, W. et al.,, Ethier, C.R., Johnson, M. & Ruberti, J.,, Hamilton, K.E. & Pye, D.C.,, Hoffman, A.S.,, Ishihara, K., Ueda, T. & Nakabayashi, N.,, Jhon, M.S. & Andrade, J.D.,, Kang-Mieler, J.J., Osswald, C.R. & Mieler, W.F.,, Kimura, H. et al.,, Kiritoshi, Y. & Ishihara, K.,, Kuppermann, B.D. & Loewenstein, A.,, Lee, H., Jhon, M. & Andrade, J.,, Lewis, A. et al.,, Lewis, A.L.,, Maurice, D.,, Monti, P. & Simonib, R.,, Morisaku, T. et al.,, Parkinson, G. et al.,, Rohindra, D., Nand, A. & Khurma,, Schlenoff, J.B.,, Shi, D.et al.,, Siggers, J.H. & Ethier, C.R.,, Skuta, G.L. et al.,, Stirbu, O. et al.,, Tomar, N. et al.,, Toris, C.B. et al.,, Tranoudis, I. & Efron, N.,, Vashist, A. et al.,, Weinreb, R.N. & Khaw, P.T.,, Young, G. et al.,   +34 more
core   +2 more sources