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Bioerodible Polymers for Ocular Drug Delivery
Critical Reviews in Therapeutic Drug Carrier Systems, 1998Development of ophthalmic drug-delivery systems has always been challenging. The commonly used route for drug delivery to the anterior segment of the eye has been the conjunctival cul-de-sac. Because of drawbacks associated with this route, new approaches have been investigated for delivery of drugs to the eye by means of polymeric delivery systems ...
Deshpande, Arati +2 more
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Designing dendrimers for ocular drug delivery
European Journal of Medicinal Chemistry, 2010New series of phosphorus-containing dendrimers, having one quaternary ammonium salt as core and carboxylic acid terminal groups have been synthesized from generation 0 (3 carboxylic acid terminal groups) to generation 2 (12 carboxylic acid terminal groups). These dendrimers react with the neutral form of carteolol (an ocular anti-hypertensive drug used
Grégory, Spataro +7 more
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Ophthalmologists and drug delivery scientists face considerable challenges in the realm of ocular drug delivery, primarily attributable to the intricate structural and barrier complexities inherent in the eye. The presence of various barriers, including the multilayered cornea, sclera, conjunctival blood flow, and tear dilution, imposes limitations on ...
Harshilkumar S. Jani +3 more
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Harshilkumar S. Jani +3 more
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Recent developments in ocular drug delivery
Journal of Drug Targeting, 2015Ocular drug delivery has many challenges due to the inherent physiology and natural barriers. Traditionally used eye drops are fairly inefficient with low ocular bioavailability, and drug delivery to the back of the eye currently requires invasive measures, such as implants or frequent intravitreal injections.
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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Cyclodextrin-based ocular drug delivery systems: A comprehensive review
Coordination Chemistry Reviews, 2023Bo Tang
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Targeted drug delivery strategies for precision medicines
Nature Reviews Materials, 2021Mandana T Manzari +2 more
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