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Immunotherapy of Ocular Myasthenia Gravis Reduces Conversion to Generalized Myasthenia Gravis
Journal of Neuro-Ophthalmology, 2003Several retrospective studies have suggested that immunotherapy, including prednisolone, azathioprine and thymectomy, reduces progression of ocular myasthenia gravis to generalized myasthenia gravis. This study examines the effect of immunotherapy on generalization rates in ocular myasthenia patients who are acetylcholine receptor (AChR) antibody ...
Jared, Mee +5 more
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Therapeutic options in ocular myasthenia gravis
Neuromuscular Disorders, 2001The term ocular myasthenia gravis refers to the disease clinically restricted to extrinsic ocular muscles. It can be disabling as ptosis, and to a greater extent diplopia, both interfere with daily activities. Although ocular disturbances are the most frequent initial complaints in myasthenic patients, symptoms usually progress to generalized disease ...
A, Evoli +4 more
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Journal of the National Medical Association, 1994
Ocular dysfunction accounts for nearly 70% of the initial manifestations of myasthenia gravis. Since the prevalence rate of myasthenia gravis is two to 10 cases per 100,000 population, it is important for clinicians to be cognizant of this disorder and its varied ocular presentations.
G A, March, L N, Johnson
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Ocular dysfunction accounts for nearly 70% of the initial manifestations of myasthenia gravis. Since the prevalence rate of myasthenia gravis is two to 10 cases per 100,000 population, it is important for clinicians to be cognizant of this disorder and its varied ocular presentations.
G A, March, L N, Johnson
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Treatment of ocular symptoms in myasthenia gravis
Neurology, 2008The choice between acetyl-cholinesterase inhibitors (AChE-Is) and steroids as symptomatic therapy for ocular symptoms in myasthenia is controversial.Thirty-five patients with myasthenia and ocular symptoms were evaluated by a single investigator. The ocular-quantitative myasthenia gravis (QMG) score was determined at each visit.
Minal J, Bhanushali +2 more
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Myasthenia Gravis: Systemic and Ocular Considerations
Ophthalmology, 1979In the early 1930s, the neuromuscular junction was identified as the site of the abnormality in myasthenia gravis, based on the response of patients to anticholinesterase medication.3 It has since become apparent that acetylcholine, the natural transmitter, is synthesized chiefly in the motor nerve terminals4 and is stored in vesicles for subsequent ...
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Peribulbar Corticosteroids for Ocular Myasthenia Gravis
Journal of Neuro-OphthalmologyBackground: Ocular myasthenia gravis is treated predominantly by oral medications, with the potential for systemic adverse effects. Successful treatment has been achieved using peribulbar dexamethasone. We assessed the effect of peribulbar dexamethasone or triamcinolone (40-mg Triesence), a longer-acting corticosteroid ...
Rachel Lasry +2 more
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Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 2013
Ocular myasthenia gravis, although clinically often characterized by typical classical features, can cause considerable diagnostic problems. This article aims to provide a pragmatic approach to the pathogenesis, clinical features, diagnostics and therapeutic strategies in the clinical routine.
S, Pitz, B, Jordan, S, Zierz
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Ocular myasthenia gravis, although clinically often characterized by typical classical features, can cause considerable diagnostic problems. This article aims to provide a pragmatic approach to the pathogenesis, clinical features, diagnostics and therapeutic strategies in the clinical routine.
S, Pitz, B, Jordan, S, Zierz
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Ocular Response to Corticotropin in Myasthenia Gravis
Archives of Ophthalmology, 1973Twenty-two patients who had myasthenia gravis with ptosis, ophthalmoparesis, or both, were treated with massive doses of corticotropin (adrenocorticotrophic hormone). The ocular symptoms in eight of the patients improved significantly. Subsequently, four patients who failed to improve with corticotropin therapy had thymectomies, followed by ...
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