Results 91 to 100 of about 259,165 (312)

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

The importance of incorporating technological advancements into the artificial eye process: a perspective commentary [PDF]

, 2017
Application of technology into healthcare has typically been targeted to high demand illnesses and treatments. However, with an increasing need to meet patient’s expectations combined with increased accessibility and reduced costs, smaller healthcare ...
Chinnery, H., Dyer, B., Noroozi, S., Rees, K., Thompson, S. B. N.   +4 more
core  

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Evaluation of the Performance of an Ocular Surface Modulator Containing ST-Lysyal Versus Hyaluronic Acid Eyedrops in Patients with Dry Eye Disease: A Pilot Study

Ophthalmology and Therapy
Introduction Dry eye disease (DED) is a multifactorial condition of the ocular surface, primarily treated with tear substitutes, which do not fully restore natural tear functions.
Stefano Barabino, Andrea Rosa, Sara Marini, Carlo Domenico Bianchi, Maurizio Rolando   +4 more
doaj   +1 more source

Eccentric lamellar keratolimbal grafts harvested with a manually guided microkeratome [PDF]

, 2007
Background: To perform lamellar keratolimbal allograft transplantation in a one- step procedure with a single graft, we investigated the feasibility of harvesting eccentric lamellar keratolimbal grafts from conventionally processed corneoscleral buttons ...
A. Kampik, Behrens A, Carlo Lackerbauer, Chen JJY, Chen JJY, Chuck RS, Cotsarelis G, Davanger M, Dua HS, Dua HS, Espana EM, Friend J, Grueterich M, Holland EJ, Holland EJ, Huang AJW, Kenneth R. Kenyon, Kenyon KR, Lavker RM, Martin Grueterich, Puangsricharern V, Reinhard T, Schermer A, Shimmura S, Siegfried Priglinger, Sundmacher R, Sundmacher R, Sundmacher R, Tsai RJF, Tseng SCG, Tsubota K, Tungsiripat T, Ulrich Welge-Luessen, Zieske JD   +33 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Neotropical Cerambycidae (Coleoptera) primarily in the Canadian Museum of Nature, Ottawa. I. Falsamblesthiini (Lamiinae) [PDF]

, 2010
The following new species are described: Nyctonympha andersoni, sp. n., and N. howdenarum, sp. n., both from Colombia; N. genieri, sp. n., from Ecuador; N. taeniata, sp. n., from Trinidad; Falsamblesthis microps, sp.
Galileo, Maria Helena M., Martins, Ubirajara R.   +1 more
core  

Tetracycline Actions Relevant to Rosacea Treatment [PDF]

, 2009
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Single cell analysis of short-term dry eye induced changes in cornea immune cell populations

Frontiers in Medicine
BackgroundDry eye causes corneal inflammation, epitheliopathy and sensorineural changes. This study evaluates the hypothesis that dry eye alters the percentages and transcriptional profiles of immune cell populations in the cornea.MethodsDesiccating ...
Jehan Alam, Ebru Yaman, Gerda Cristal Villalba Silva, Rui Chen, Cintia S. de Paiva, Mary Ann Stepp, Stephen C. Pflugfelder   +6 more
doaj   +1 more source