Inflammation and dry eye disease—where are we? [PDF]
The presence of inflammation in dry eye disease (DED) results in increased patient symptomatology, ocular surface damage and worsening tear dysfunction.
Srinivas K Rao +4 more
doaj +1 more source
Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine [PDF]
In the field of predictive, preventive and personalised medicine, researchers are keen to identify novel and reliable ways to predict and diagnose disease, as well as to monitor patient response to therapeutic agents.
A Acera +183 more
core +2 more sources
Factors associated with ocular surface epithelial damage in patients with primary Sjögren’s syndrome
Background The aim of this study was to evaluate the effects of systemic parameters, laboratory findings, oral parameters, and other ocular surface parameters on ocular surface epithelial damage in patients with primary Sjögren’s syndrome (pSS).
Ji Eun Kim +5 more
doaj +1 more source
Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]
The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz +14 more
core +1 more source
Bilateral limbal stem cell deficiency with xeroderma pigmentosum in a young Asian child
Key Clinical Message Xeroderma pigmentosum is an autosomal recessive disorder with various ocular manifestations of which bilateral limbal stem cell deficiency is a rare manifestation.
Bharat Gurnani, Kirandeep Kaur
doaj +1 more source
Comparison of the NEI-VFQ and OSDI questionnaires in patients with Sjögren's syndrome-related dry eye [PDF]
Background To examine the associations between vision-targeted health-related quality of life (VT-HRQ) and ocular surface parameters in patients with Sjögren's syndrome, a systemic autoimmune disease characterized by dry eye and dry mouth.
Smith Janine A +3 more
core +2 more sources
A novel technique of contrast-enhanced optical coherence tomography imaging in evaluation of clearance of lipids in human tears [PDF]
Purpose: The aim of this work was to gather preliminary data in different conditions of healthy eyes, aqueous tear deficient dry eyes, obstructive meibomian gland disease (MGD) and non-obvious obstructive MGD (NOMGD) individuals, using a new, contrast ...
Coronella Franco +3 more
core +1 more source
OBJECTIVE: The purpose of this study was to ascertain the extent to which the ocular surface of women with polycystic ovary syndrome is impacted. STUDY DESIGN: Included in this case-control study were 23 eyes of 23 patients (Group I) with polycystic ...
Demet Yabanoglu, Funda Gode
doaj +1 more source
Biomarkers in ocular chronic graft versus host disease: tear cytokine- and chemokine-based predictive model. [PDF]
Producción CientíficaPurpose: To develop a tear molecule level-based predictive model based on a panel of tear cytokines and their correlation with clinical features in ocular chronic graft versus host disease (cGVHD).
Caballero, Dolores +10 more
core +2 more sources
Pro-Secretory Activity and Pharmacology in Rabbits of an Aminophenyl-1,3,5-Triazine CFTR Activator for Dry Eye Disorders. [PDF]
PurposePharmacological activation of ocular surface cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels is a potential pro-secretory approach to treat dry eye disorders.
Felix, Christian M +3 more
core +2 more sources

