Results 61 to 70 of about 861,821 (161)

Orthodentine‐osteodentine and osteocytic‐anosteocytic transition inferred from Silurian stem chondrichthyan dermal jawbones with ever‐white teeth overgrown by brown denticles

Developmental Dynamics, EarlyView.
Abstract Background The dentigerous jawbones of a 423‐million‐year‐old stem chondrichthyan (ischnacanthid acanthodian) carry a characteristic combination of multi‐row non‐shedding white teeth with brownish overgrowing denticles. The color distinction makes it a good model for observing the interaction between two odontode lineages, but the nature of ...
Jia‐Cih Kang, Henning Blom, Tiiu Märss, Donglei Chen   +3 more
wiley   +1 more source

Different from bone: Tooth formation and enameloid mineralization are not affected by reduced dietary phosphorus intake

Developmental Dynamics, EarlyView.
Abstract Background Vertebrates rely on phosphorus intake for skeletal mineralization. In humans, hypomineralized teeth associated with rickets, hypophosphatemia, hypophosphatasia, or idiopathic molar‐incisor‐hypomineralization pose significant problems.
S. Cotti, A. Huysseune, I. A. K. Fiedler, B. Busse, C. Di Biagio, M. Rücklin, F. Marone, A. Forlino, P. E. Witten   +8 more
wiley   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

DMP1 and DSP localization during in vitro odontoblast like cell differentiation [PDF]

, 2012
The aim of this study was to analyze the temporal and spatial localization of dentin matrix protein 1 (DMP1) and dentin sialoprotein (DSP) in human dental pulp cells differentiated in vitro towards odontoblast-like cells. Following to a notable injury to
NICOLINI, BENEDETTA, FALCONI, MIRELLA, Giovanna Orsini, Orsini, Giovanna, TETI, GABRIELLA, RUGGERI, ALESSANDRA, BRESCHI, LORENZO   +6 more
core   +1 more source

The Effect of Hydrogel Hyaluronic Acid on Dentine Sialophosphoprotein Expression of Human Dental Pulp Stem Cells

European Endodontic Journal, 2023
Objective: Hyaluronic acid (HA) is glycosaminoglycan and one of important factors in extracellular matrix. In an inflamed pulp, when niche biology is conducive, the recruitment of human dental pulp stem cells (hDPSCs) will take place and differentiate ...
Valonia Irene Nugraheni, Dini Asrianti Bagio, Anggraini Margono, Indah Julianto   +3 more
doaj   +1 more source

Synergistic Effects of Bacterial Mimetic and Mechanical Stimulation in Dental Pulp Cell Inflammatory Signalling: A Laboratory Investigation

International Endodontic Journal, EarlyView.
ABSTRACT Objectives Mechanical and/or microbial stimuli can prompt extracellular ATP release in many cell types, where it acts as an inflammatory mediator to amplify pain signals and inflammation. This study aimed to investigate the synergistic effects of microbial and/or mechanical stimulation on ATP and cytokine release from dental pulp cells (DPCs ...
Orla M. Dunne, Lorcan P. McGarvey, Imad About, Fionnuala T. Lundy, Ikhlas El‐Karim   +4 more
wiley   +1 more source

LincRNA-ASAO promotes dental pulp repair through interacting with PTBP1 to increase ALPL alternative splicing

Stem Cell Research & Therapy
Background Alternative splicing not only expands the genetic encoding of genes but also determines cellular activities. This study aimed to elucidate the regulation mechanism and biological functions of lincRNA-ASAO in the process of odontogenesis ...
Fuchun Fang, Xiaolan Guo, Sitong Liu, Longrui Dang, Zehao Chen, Yumeng Yang, Lu Chen, Jiahao Lin, Wei Qiu, Zhao Chen, Buling Wu   +10 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Experimental Induction of Odontoblast Differentiation and Stimulation During Preparative Processes [PDF]

, 1993
In vivo implantation experiments have shown that ethylenediaminetetraaceticacid(EDTA)-soluble frac tions of dentin stimulate reparative dentinogenesis .
Cassidy, N., Ruch, J. V., Meyer, J. M., Begue-Kirn, C., Kubler, M. D., Smith, A. J., Lesot, H.   +6 more
core   +1 more source

Evaluation of odonto/osteogenic differentiation potential from different regions derived dental tissue stem cells and effect of 17β-estradiol on efficiency

BMC Oral Health, 2021
Background The dentin is a tissue, which is formed by odontoblasts at the pulp interface of the teeth that supports the enamel. Odontoblasts, the cranial neural crest cells are derived from ectodermal mesenchymal stem cells (MSCs) and are long and ...
Young-Bum Son, Young-Hoon Kang, Hyeon-Jeong Lee, Si-Jung Jang, Dinesh Bharti, Sung-Lim Lee, Byeong-Gyun Jeon, Bong-Wook Park, Gyu-Jin Rho   +8 more
doaj   +1 more source