Chromatin Remodeller BRD9 Orchestrates Odontoblastic Differentiation via Coordinating RUNX2-KLF4. [PDF]
Cell ProlifDuring odontoblast lineage commitment, the chromatin remodeller BRD9 acts as a critical epigenetic coordinator, orchestrating the chromatin landscape to facilitate synergistic binding of key transcription factors RUNX2 and KLF4 to target loci for odontogenesis.
Zeng W +8 more
europepmc +2 more sources
Histological evaluation of pulpal healing following direct pulp capping with polytetrafluoroethylene or melatonin, with or without adjunctive low-level laser therapy in Wistar rat molars. [PDF]
Sci RepThis study evaluated pulpal healing following direct pulp capping with polytetrafluoroethylene (PTFE) or melatonin (MEL), with or without adjunctive low-level laser therapy (LLLT), in Wistar rat molars.
Abdelaziz SA +4 more
europepmc +2 more sources
Cellular Dynamics and Dentine Bridge Formation Following Direct Pulp Capping With MTA and Biodentine in a Murine Model. [PDF]
Int Endod JABSTRACT Aim Formation of a mineralized dentine bridge is the hallmark of successful direct pulp capping (DPC). Mineral trioxide aggregate (MTA) and Biodentine are widely used capping materials, but in vivo evidence comparing their regenerative potential remains inconclusive. This study used a controlled murine model to compare dentine bridge formation
Sajdeya A +4 more
europepmc +2 more sources
Histological investigation of the effects of chitosan and 3 different pulpotomy agents on rat dental pulps. [PDF]
BMC Oral HealthBackground Pulpotomy is a vital pulp therapy performed following the removal of infected or affected coronal pulp. However, there is no consensus on the most effective pulpotomy agent.
Pedük K +5 more
europepmc +2 more sources
The Thickness of Odontoblast-Like Cell Layer After Induced by Propolis Extract and Calcium Hydroxide
Dental Journal, 2016 Background: Propolis is a substance made from resin collected by bees (Apis mellifera) from variety of plants, mixed with its saliva and various enzymes to build a nest.
Irfan Dwiandhono +2 more
exaly +3 more sources
Soluble Notch agonist enables human ameloblast maturation and enamel-like tissue formation for tooth regeneration. [PDF]
Int J Oral SciEnamel, the hardest mineralized material in the human body, protects the underlying living tissues, the dentin and pulp of the tooth. However, over 90% of adults have lost or damaged enamel and cannot regenerate the protective structure due to lack of ...
Patni AP +15 more
europepmc +2 more sources
A histopathological case-control study of severe turner teeth and normal teeth: structural and compositional alterations in pulp and periodontal tissues. [PDF]
BMC Oral HealthObjective Turner teeth are developmental defects of permanent teeth commonly associated with disturbances affecting the corresponding primary predecessors, particularly infection or trauma. Although their clinical features have been described in previous
Di T +6 more
europepmc +2 more sources
Laminin-Modified Dental Pulp Extracellular Matrix for Dental Pulp Regeneration
Frontiers in Bioengineering and Biotechnology, 2021 Native dental pulp extracellular matrix (DPEM) has proven to be an effective biomaterial for dental pulp regeneration. However, as a significant extracellular matrix glycoprotein, partial laminins were lost during the decellularization process, which ...
Jiahui Fu +8 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2020 Objective: To find out the depth dependent heat effect of Diamond and Carbide burs on odontoblast layer and processes of premolar teeth. Study Design: Laboratory based experimental study.
Nabila Momin +3 more
doaj +4 more sources
Scientific Reports, 2023 Ascorbic acid (AA; vitamin C) plays a crucial role in the biosynthesis and secretion of collagen to produce the organic matrix of hard tissues. Nevertheless, the detailed mechanism by which AA induces reparative dentinogenesis is still unknown.
Naoto Ohkura +6 more
doaj +1 more source