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Odontoblasts in odontogenic tumors
Medical Hypotheses, 2013Odontoblasts are secretory cells displaying epithelial and mesenchymal features, which exist in a monolayer at the interface between the dentin and pulp of a tooth. During embryogenesis, these cells form a dentin shell and throughout life continue to produce dentin while, also acting as sensor cells helping to mediate tooth sensitivity. In this process,
Nadine C, Milos +2 more
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Experimental Cell Research, 2014
Odontoblasts are post-mitotic cells organized as a layer of palisade cells along the interface between the dental pulp and dentin. They are responsible for the formation of the physiological primary and secondary dentins. They synthesize the organic matrix of type I collagen and actively participate to its mineralization by secreting proteoglycans and ...
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Odontoblasts are post-mitotic cells organized as a layer of palisade cells along the interface between the dental pulp and dentin. They are responsible for the formation of the physiological primary and secondary dentins. They synthesize the organic matrix of type I collagen and actively participate to its mineralization by secreting proteoglycans and ...
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Nucleoli of human odontoblasts
Archives of Oral Biology, 1972Abstract Nucleoli of human odontoblasts were studied in smears stained with buffered toluidine blue at pH 5, for the demonstration of RNP-containing structures, including nucleoli. The odontoblasts were obtained from 5 premolars removed for orthodontic reasons.
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Odontoblast: a mechano‐sensory cell
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, 2008AbstractOdontoblasts are organized as a single layer of specialized cells responsible for dentine formation and presumably for playing a role in tooth pain transmission. Each cell has an extension running into a dentinal tubule and bathing in the dentinal fluid.
Henry, Magloire +4 more
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Odontoblast commitment and differentiation
Biochemistry and Cell Biology, 1998Histological and cytological organization confer specificity to the odontoblasts. These postmitotic, neural crest derived, polarized cells are aligned in a single layer at the periphery of the dental pulp and secrete the organic components of predentin-dentin.
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Epigenetic Signals during Odontoblast Differentiation
Advances in Dental Research, 2001Odontoblast terminal differentiation occurs according to a tooth-specific pattern and implies both temporo-spatially regulated epigenetic signaling and the expression of specific competence. Differentiation of odontoblasts (withdrawal from the cell cycle, cytological polarization, and secretion of predentin/dentin) is controlled by the inner dental ...
LESOT H +5 more
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Structure and organization of odontoblasts
The Anatomical Record, 1996Differentiation of odontoblasts involves cell-to-cell recognition, contact stabilization involving the formation of attachment specializations, cytoplasmic polarization, development of the protein synthetic and secretory apparatus, and the active transport of mineral ions.
T, Sasaki, P R, Garant
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Expression of amelogenin in odontoblasts
Bone, 2003Amelogenin is the major enamel protein produced by ameloblasts. Its expression has been shown to be down-regulated in ameloblasts of vitamin-D-deficient (-D) rats. The potential expression and localization of amelogenin in odontoblasts and its regulation by vitamin D were investigated in this study.
P, Papagerakis +5 more
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Journal of Dental Research, 2013
Odontoblasts are dentin-secreting cells that survive for the whole life of a healthy tooth. Once teeth are completely erupted, odontoblasts transform into a mature stage that allows for their functional conservation for decades, while maintaining the capacity for secondary and reactionary dentin secretion.
E, Couve, R, Osorio, O, Schmachtenberg
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Odontoblasts are dentin-secreting cells that survive for the whole life of a healthy tooth. Once teeth are completely erupted, odontoblasts transform into a mature stage that allows for their functional conservation for decades, while maintaining the capacity for secondary and reactionary dentin secretion.
E, Couve, R, Osorio, O, Schmachtenberg
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Cathepsind activity in isolated odontoblasts
Calcified Tissue Research, 1977The presence of an acid proteinase with a high activity has been demonstrated in isolated odontoblast-predentine material from dentinogenically active rat incisors. The enzyme was identified as cathepsin D (EC 3.4.23.5). The possible significance of the enzymatic degradation of proteoglycans and glycosaminoglycans in the course of the calcification ...
A, Linde, B, Persliden
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