Results 51 to 60 of about 9,324 (181)

Orthodentine‐osteodentine and osteocytic‐anosteocytic transition inferred from Silurian stem chondrichthyan dermal jawbones with ever‐white teeth overgrown by brown denticles

Developmental Dynamics, EarlyView.
Abstract Background The dentigerous jawbones of a 423‐million‐year‐old stem chondrichthyan (ischnacanthid acanthodian) carry a characteristic combination of multi‐row non‐shedding white teeth with brownish overgrowing denticles. The color distinction makes it a good model for observing the interaction between two odontode lineages, but the nature of ...
Jia‐Cih Kang, Henning Blom, Tiiu Märss, Donglei Chen   +3 more
wiley   +1 more source

Atlas of human dental pulp cells at multiple spatial and temporal levels based on single-cell sequencing analysis

Frontiers in Physiology, 2022
The dental pulp plays a crucial role in the long-term maintenance of tooth function. The progress of endodontic treatment and pulp tissue regeneration engineering has made pulp-regeneration therapy promising in clinical practice.
Huihui Ren, Quan Wen, Qingxuan Zhao, Nan Wang, Yuming Zhao   +4 more
doaj   +1 more source

Endogenous Trigeminal Neurons Induce Schwann Differentiation of Donor Stem Cells in Dental Pulp Regeneration via Reciprocal Extracellular Vesicles Interplay

Exploration, EarlyView.
Our study demonstrates that the host TG coordinates with heterologously implanted SHED to regenerate functional dental pulp through reciprocal EVs’ interplay. EVs derived from implanted stem cells migrate to the host TG to activate axonal regeneration.
Wanmin Zhao, Wenzhe Wang, Jia Guo, Jiani Liu, Wei Wang, Dihao Tao, Jiayi Dong, Zhonghan Li, Shiyu Liu, Songtao Shi, Tao Chen, Yan Jin, Bei Li   +12 more
wiley   +1 more source

Amelogenin Gene Expression in Porcine Odontoblasts

, 2002
Amelogenin is the major organic component in the enamel matrix of developing teeth and plays an important role in enamel biomineralization. Amelogenin has been reported to be a specific secretory product of ameloblasts.
S. Oida, Y. Yamakoshi, H. Ando, M. Yamada, M. Fukae, T. Nagano   +5 more
core   +1 more source

Chitin scaffolds derived from the marine demosponge Aplysina fistularis stimulate the differentiation of dental pulp stem cells

Frontiers in Bioengineering and Biotechnology, 2023
The use of stem cells for tissue regeneration is a prominent trend in regenerative medicine and tissue engineering. In particular, dental pulp stem cells (DPSCs) have garnered considerable attention.
Anna Zawadzka-Knefel, Agnieszka Rusak, Monika Mrozowska, Tomasz Machałowski, Andrzej Żak, Katarzyna Haczkiewicz-Leśniak, Michał Kulus, Piotr Kuropka, Marzenna Podhorska-Okołów, Katarzyna Skośkiewicz-Malinowska   +9 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Odontoblasts or odontocytes, expression of stem cells markers and differentiation markers among human adult odontoblasts

Saudi Dental Journal
Objective: Despite that, the odontoblasts of the dental pulp are considered a terminally differentiated type of cell. We were interested in investigating if they express any embryonic, mesenchymal, or neural stem cell markers, along with other ...
Heba Alzer, Firas Alsoleihat
doaj   +1 more source

Rare Novel Genetic Variants of the OFD1 Gene Associated With a Familial Form and a Sporadic Case of Long Bone Atypical Fractures

Clinical Genetics, EarlyView.
A novel rare variant of the OFD1 gene was identified in a family with dental hypoplasia, facial hypoplasia, and adult‐onset multiple atypical fractures of long bones. Another variant of the OFD1 gene was found in a woman with bisphosphonate‐associated atypical femur fracture.
Marie‐Ève Boisvert, Halim Maaroufi, Rachel Laframboise, Frédéric Fournier, Suzanne N. Morin, Edith Gagnon, Claudia Gagnon, Fabrice Mac‐Way, Mahmoud Rouabhia, Louis‐Georges Ste‐Marie, Arnaud Droit, Jacques P. Brown, Laëtitia Michou   +12 more
wiley   +1 more source

Histopathological pulp response of dog's teeth capped with biosealer and biodentine: An in vivo study

Saudi Endodontic Journal, 2020
Introduction: The aim of this study was to evaluate the pulpal response after pulp capping using either biodentine (BD) or tech biosealer capping (TBC) in the dog model.
Inas M Al-Sherbiny, Ashraf M Abu-Seida, Mona H Farid, Inas T Motawea, Hagar A Bastawy   +4 more
doaj   +1 more source

Synergistic Effects of Bacterial Mimetic and Mechanical Stimulation in Dental Pulp Cell Inflammatory Signalling: A Laboratory Investigation

International Endodontic Journal, EarlyView.
ABSTRACT Objectives Mechanical and/or microbial stimuli can prompt extracellular ATP release in many cell types, where it acts as an inflammatory mediator to amplify pain signals and inflammation. This study aimed to investigate the synergistic effects of microbial and/or mechanical stimulation on ATP and cytokine release from dental pulp cells (DPCs ...
Orla M. Dunne, Lorcan P. McGarvey, Imad About, Fionnuala T. Lundy, Ikhlas El‐Karim   +4 more
wiley   +1 more source