Journal of Tissue Engineering, 2023 The odontogenic differentiation of dental pulp stem cells (DPSCs), which is vital for tooth regeneration, was regulated by various functional molecules.
Tao Jiang +5 more
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Frontiers in Genetics, 2020 Osteo/odontogenic differentiation is a key process of human stem cells from apical papilla (SCAP) in tooth root development. Emerging evidence indicates microRNAs (miRNAs) play diverse roles in osteogenesis.
Junqing Liu +9 more
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Synergistic effects of collagen membrane and mineral trioxide aggregate on odontogenic differentiation and mineralization of human dental pulp stem cells: an in vitro study [PDF]
BMC Oral HealthBackground Human dental pulp stem cells (hDPSCs) are oral-derived mesenchymal stem cells with high proliferative capacity and odontogenic differentiation potential, making them relevant for dental pulp and dentin–pulp complex regeneration.
Nermine Hassan +2 more
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Protein Arginine Methyltransferase 6 Regulated Odontogenic Differentiation and Mitochondrial Function of Stem Cells from Apical Papilla Through its Nuclear Localization Sequence via β-catenin Pathway [PDF]
International Dental JournalObjectives: Odontogenic differentiation of stem cells from apical papilla (SCAPs) is critical for pulp regeneration therapy. Protein arginine methyltransferase 6 (PRMT6) plays an important role in stem cell differentiation, but the specific functions and
Wanhao Yan +6 more
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H19 Promotes Odontogenic Differentiation of Human Dental Pulp Cells via miR-103a-3p-Mediated PIK3R1/AKT and KLF4 Pathways [PDF]
International Dental JournalBackground: The regeneration of functional dentin is a critical clinical goal for preserving tooth vitality after injury, with odontoblastic differentiation of human dental pulp stem cells (hDPSCs) being central to this reparative process. While the long
Jingkun Zhang +9 more
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Circ-AARS plays an important role during the odontogenic differentiation of dental pulp stem cells by modulating miR-24-3p/KLF6 expression [PDF]
Stem Cell Research & TherapyBackground Circular RNAs (circRNAs) play a crucial role in stem cell-based tooth regeneration. However, the functions and underlying mechanisms of circRNAs in tooth regeneration from human dental pulp stem cells (DPSCs) remain largely unclear. Methods In
Meizhi Sui +6 more
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hsa_circ_0001599 promotes odontogenic differentiation of human dental pulp stem cells by increasing ITGA2 expression and stability [PDF]
Communications BiologyDental pulp regeneration is significantly aided by human dental pulp stem cells (hDPSCs). An increasing number of studies have demonstrated that circular RNAs (circRNAs) are crucial in the multidirectional differentiation of many mesenchymal stem cells ...
Yeqing Yang +5 more
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In Vitro Evaluation of Odontogenic Differentiation Potential of Adipose Tissue-Derived Stem Cells in Presence and Absence of Nano-Hydroxyapatite Crystals [PDF]
The Egyptian Journal of Histology, 2023 Aim of the Study: Tissue regeneration therapy using stem cells is becoming the state of the art for dental treatment. The present study aimed to use adipose tissue-derived stem cells for odontogenic differentiation, as a more abundant replacement for ...
Asmaa Elgamal, Ahmed Fahmi
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Frontiers in Cell and Developmental Biology, 2021 Background: Tooth tissue regeneration mediated by mesenchymal stem cells (MSCs) has become the most ideal treatment. Although the known regulatory mechanism and some achievements have been discovered, directional differentiation cannot effectively induce
Ning Wang +5 more
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Stem Cells International, 2023 Objective. Human dental pulp stem cells (hDPSCs) were recognized as a suitable and promising source of stem cells in dental pulp regeneration. However, the mechanism by which hDPSCs differentiation into osteo-/odontogenic lineage remains unclear.
Kangrui Zeng +5 more
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