Results 1 to 10 of about 4,117 (183)

Ethylenediaminetetraacetic Acid and Other Dentine Bioactive Molecule‐Releasing Agents for Regenerative Endodontic Procedures: A Systematic Review

International Endodontic Journal, EarlyView.
ABSTRACT Background The bioactive molecules released from dentine are key to stem‐cell recruitment, proliferation and differentiation in regenerative endodontics. However, there is limited and conflicting information regarding current and potential agents for releasing dentine bioactive molecules for regenerative endodontic procedures.
Arwa Al‐Maswary, Xiaoxuan Deng, Haizal M. Hussaini, Lara T. Friedlander, Paul R. Cooper   +4 more
wiley   +1 more source

Noncanonical Wnt5a Signaling Suppresses Hippo/TAZ-Mediated Osteogenesis Partly Through the Canonical Wnt Pathway in SCAPs

Drug Design, Development and Therapy, 2022
Yajing Fu,1 Dan Ma,2 Fengyan Fan,3 Tongke Sun,1 Ruiqi Han,1 Yanran Yang,1 Jun Zhang1 1Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration ...
Fu Y, Ma D, Fan F, Sun T, Han R, Yang Y, Zhang J   +6 more
doaj  

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Roles of basic fibroblast growth factor, stem cells from dental pulp and apical papilla in the repair and regeneration of dental pulp and other tissues/organs

Journal of Dental Sciences
Currently, the concept of regeneration and regenerative therapies are already being applied clinically to treat pulpal and periodontal diseases, as well as to repair and regenerate systemic organs and tissues.
Pin-Hsuan Wu, Yan-Hsiung Wang, Ying-Chu Lin, Ya-Shuan Chou, Mei-Chi Chang, Jiiang-Huei Jeng   +5 more
doaj   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

m6A-Modified GATA2 Enhances Odontogenic Differentiation in Stem Cells from the Apical Papilla

International Journal of Molecular Sciences
Epigenetic modifications play a crucial role in regulating stem cell differentiation. Among these, N6-methyladenosine (m6A) modification significantly impacts mRNA stability and translation. However, its role in dental stem cell differentiation remains largely unexplored.
Haoqing Yang, Fengning Yuan, Jiaxin Song, Yishu Huang, Zhaochen Shan, Zhipeng Fan   +5 more
openaire   +2 more sources

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Effects of different concentrations of MTA on the proliferation and differentiation of stem cells from the apical papilla

口腔疾病防治, 2018
Objective To investigate the effect of different concentrations of MTA on the proliferation and differen⁃ tiation of stem cells from the apical papilla (SCAP) and the potential of the SCAP to differentiate into odontoblasts.
NIU Qiaoli, LI Yiming, SONG Yanyan, LI Chenxi, ZHAO Jin   +4 more
doaj   +1 more source

Soft Tissue Substitutes: Current Biomaterials and Indications at Teeth and Implant Sites

Journal of Periodontal Research, EarlyView.
This manuscript provides an updated overview of the current evidence on soft tissue graft substitutes for teeth and dental implants. When appropriately indicated, these biomaterials offer a reliable, less invasive alternative to autogenous grafts, effectively improving root coverage, keratinized mucosa width, and soft tissue thickness with reduced ...
Lorenzo Tavelli, Daniel Thoma, Maria Elisa Galarraga‐Vinueza, Mario Romandini, Shayan Barootchi   +4 more
wiley   +1 more source

Dental Tissue — New Source for Stem Cells

The Scientific World Journal, 2009
Stem cells have been isolated from many tissues and organs, including dental tissue. Five types of dental stem cells have been established: dental pulp stem cells, stem cells from exfoliated deciduous teeth, stem cells from apical papilla, periodontal ...
Vladimir Petrovic, Vladisav Stefanovic
doaj   +1 more source