Results 21 to 30 of about 4,117 (183)

Stem Cells From the Apical Papilla (SCAP) as a Tool for Endogenous Tissue Regeneration [PDF]

Frontiers in Bioengineering and Biotechnology, 2018
Stem cells extracted from developing tissues possibly exhibit not only unique but also superior traits against their developed counterparts. Indeed, stem cells from the apical papilla (SCAP); a unique group of dental stem cells related to developing roots have been shown to be a promising tool for regenerative endodontic procedures and regeneration in ...
Ola A Nada, Rania El Backly
exaly   +4 more sources

DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013 [PDF]

Stem Cell Research & Therapy, 2020
Background Mesenchymal stem cell (MSC)-based cartilage tissue regeneration is a treatment with great potential. How to enhance the MSC chondrogenic differentiation is a key issue involved in cartilage formation.
Haoqing Yang, Yangyang Cao, Jianpeng Zhang, Yuncun Liang, Xiaomin Su, Chen Zhang, Huina Liu, Xiao Han, Lihua Ge, Zhipeng Fan   +9 more
doaj   +2 more sources

Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization [PDF]

Stem Cell Research & Therapy, 2021
Background Reconstruction of complex critical-size defects (CSD) in the craniofacial region is a major challenge, and soft tissue regeneration is crucial in determining the therapeutic outcomes of craniofacial CSD.
Yao Liu, Xueying Zhuang, Si Yu, Ning Yang, Jianhong Zeng, Xuemei Liu, Xu Chen   +6 more
doaj   +2 more sources

Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla

BMC Oral Health
Background Simvastatin modulates numerous stem cell functions, including stemness maintenance and differentiation. The present study aimed to explore the effect of simvastatin on the osteogenic differentiation of Stem Cells isolated from Apical Papilla ...
Paak Rewthamrongsris, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Prim Janjarussakul, Chatvadee Kornsuthisopon, Lakshman Samaranayake, Thanaphum Osathanon   +6 more
doaj   +3 more sources

A pilot study on biological characteristics of human CD24(+) stem cells from the apical papilla

Journal of Dental Sciences, 2022
Background/purpose: CD24 is a specific cell surface marker for undifferentiated dental stem cells from apical papilla (SCAPs) seen only during root development, before the tooth emerges through gum.
Jing Liang, Ya-Jin Zhao, Jun-Qing Li, Lan Lan, Wen-Jing Tao, Jia-Yuan Wu   +5 more
doaj   +3 more sources

Micropatterned hydrogels and cell alignment enhance the odontogenic potential of stem cells from apical papilla in-vitro. [PDF]

Dent Mater, 2020
An understanding of the extracellular matrix characteristics which stimulate and guide stem cell differentiation in the dental pulp is fundamental for the development of enhanced dental regenerative therapies. Our objectives, in this study, were to determine whether stem cells from the apical papilla (SCAP) responded to substrate stiffness, whether ...
Ha M, Athirasala A, Tahayeri A, Menezes PP, Bertassoni LE.   +4 more
europepmc   +4 more sources

Influence of Citric Acid on the Vitality of Stem Cells from Apical Papilla

Acta Medica Bulgarica, 2018
The endodontic treatment of immature permanent teeth with necrotic pulp is a serious clinical challenge. The chemical agents, used in regenerative procedures, should be selected not only based on their bactericidal/bacteriostatic properties, but also on ...
Hristov Kr., Gateva N., Stanimirov P., Ishkitiev N., Tsikandelova R., Mihaylova Z.   +5 more
doaj   +2 more sources

Stem cells from tooth apical papilla modulate fibromyalgia-like changes in mice

Brain Research Bulletin
Background: The treatment of fibromyalgia remains a current challenge. While the analgesic effects of mesenchymal stem cells have been the subject of previous research, their potential in managing fibromyalgia symptoms needs further investigation.
Ana P.A. Dagnino, Gabriel Rübensam, Jefferson B. Silva, Maria M. Campos   +3 more
doaj   +3 more sources

Functional sensory neurons derived from human stem cells from apical papilla

Indian Journal of Dental Research
Objectives: This study aimed to investigate the sensory maturation–enhancing effects of co-culturing human stem cells from apical papilla (hSCAPs)-derived neural stem cells (NSCs) with chick embryonic dorsal root ganglia (DRG) under three-dimensional (3D)
Pukit Limyothin, Thanawit Juntamongkon, Phubase Chadaratthiti, Tarinee Chodchavanchai, Amarin Thongsuk, Peeratchai Seemaung, Nisarat Ruangsawasdi, Tatcha Balit, Charoensri Thonabulsombat, Anupong T. Songsaad   +9 more
doaj   +2 more sources

EVALUATION OF THE ADHESION AND MORPHOLOGY OF STEM CELLS FROM APICAL PAPILLA IN DIRECT CONTACT WITH MTA AND BIODENTINE [PDF]

Journal of IMAB, 2022
Purpose: To investigate the use of tricalcium silicate cement Biodentine as an alternative to MTA in regenerative endodontic procedures by assessing the morphology and adhesion of stem cells from apical papilla in direct contact with these materials ...
Krasimir Hristov, Nikolay Ishkitiev, Marina Miteva, Nataliya Gateva   +3 more
doaj   +1 more source