Functional sensory neurons derived from human stem cells from apical papilla
Objectives: This study aimed to investigate the sensory maturation–enhancing effects of co-culturing human stem cells from apical papilla (hSCAPs)-derived neural stem cells (NSCs) with chick embryonic dorsal root ganglia (DRG) under three-dimensional (3D)
Pukit Limyothin +9 more
doaj +2 more sources
Isolation and Culture of Human Stem Cells from Apical Papilla under Low Oxygen Concentration Highlight Original Properties. [PDF]
International audienceStem cells isolated from the apical papilla of wisdom teeth (SCAPs) are an attractive model for tissue repair due to their availability, high proliferation rate and potential to differentiate in vitro towards mesodermal and ...
Rémy M +8 more
europepmc +2 more sources
Micropatterned hydrogels and cell alignment enhance the odontogenic potential of stem cells from apical papilla in-vitro [PDF]
An understanding of the extracellular matrix characteristics which stimulate and guide stem cell differentiation in the dental pulp is fundamental for the development of enhanced dental regenerative therapies. Our objectives, in this study, were to determine whether stem cells from the apical papilla (SCAP) responded to substrate stiffness, whether ...
Michael Ha +4 more
openaire +4 more sources
EVALUATION OF THE ADHESION AND MORPHOLOGY OF STEM CELLS FROM APICAL PAPILLA IN DIRECT CONTACT WITH MTA AND BIODENTINE [PDF]
Purpose: To investigate the use of tricalcium silicate cement Biodentine as an alternative to MTA in regenerative endodontic procedures by assessing the morphology and adhesion of stem cells from apical papilla in direct contact with these materials ...
Krasimir Hristov +3 more
doaj +1 more source
Effects of ethylenediaminetetraacetic acid on stem cells from the apical papilla: In vitro study
Ethylenediaminetetraacetic acid (EDTA) is used as an irrigant in regenerative endodontic treatment. The present study aimed to investigate the effects of EDTA on stem cells from apical papilla (SCAPs) in vitro.Human SCAPs were isolated and characterised. The cells were treated with media supplemented with EDTA at concentrations ranging from 1.25% to 17%
Suphalak Phothichailert +6 more
openaire +6 more sources
Neural Regenerative Potential of Stem Cells Derived from the Tooth Apical Papilla [PDF]
The regenerative effects of stem cells derived from dental tissues have been previously investigated. This study assessed the potential of human tooth stem cells from apical papilla (SCAP) on nerve regeneration. The SCAP collected from nine individuals were characterized and polarized by exposure to interferon-γ (IFN-γ).
Ana Paula Aquistapase, Dagnino +8 more
openaire +2 more sources
Mesenchymal stem cell-mediated functional tooth regeneration in swine. [PDF]
Mesenchymal stem cell-mediated tissue regeneration is a promising approach for regenerative medicine for a wide range of applications. Here we report a new population of stem cells isolated from the root apical papilla of human teeth (SCAP, stem cells ...
Wataru Sonoyama +10 more
doaj +1 more source
Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy
Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages. Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can be used as an alternative to ...
Jun Kang +4 more
openaire +3 more sources
Stem cells from the apical papilla (SCAPs) are promising candidates for regenerative endodontic treatment and tissue regeneration in general. However, harvesting enough cells from the limited apical papilla tissue is difficult, and the cells lose their ...
Qianyu Cheng +14 more
doaj +1 more source
Objective: Indirect Jagged1 immobilization efficiently activates canonical Notch signaling in human dental pulp stem cells (hDPSCs). This study aimed to investigate the characteristics of the Jagged1-treated hDPSC-derived decellularized extracellular ...
Suphalak Phothichailert +9 more
doaj +1 more source

