Results 21 to 30 of about 4,536 (207)

Micropatterned hydrogels and cell alignment enhance the odontogenic potential of stem cells from apical papilla in-vitro. [PDF]

Dent Mater, 2020
An understanding of the extracellular matrix characteristics which stimulate and guide stem cell differentiation in the dental pulp is fundamental for the development of enhanced dental regenerative therapies. Our objectives, in this study, were to determine whether stem cells from the apical papilla (SCAP) responded to substrate stiffness, whether ...
Ha M, Athirasala A, Tahayeri A, Menezes PP, Bertassoni LE.   +4 more
europepmc   +4 more sources

Influence of Citric Acid on the Vitality of Stem Cells from Apical Papilla

Acta Medica Bulgarica, 2018
The endodontic treatment of immature permanent teeth with necrotic pulp is a serious clinical challenge. The chemical agents, used in regenerative procedures, should be selected not only based on their bactericidal/bacteriostatic properties, but also on ...
Hristov Kr., Gateva N., Stanimirov P., Ishkitiev N., Tsikandelova R., Mihaylova Z.   +5 more
doaj   +2 more sources

Exploring the potential of stem cells from the apical papilla (SCAPs) in regenerative medicine: advantages, applications, challenges and opportunities [PDF]

Stem Cell Research & Therapy
Stem cells from the apical papilla (SCAPs) represent a unique population of mesenchymal stem cells (MSCs) located in the apical papilla of immature permanent teeth.
Mengyu Huang, Waruna Lakmal Dissanayaka, Cynthia KY YIU   +2 more
doaj   +2 more sources

The Journey of SCAPs (Stem Cells from Apical Papilla), from Their Native Tissue to Grafting: Impact of Oxygen Concentration. [PDF]

Cells, 2022
Tissue engineering strategies aim at characterizing and at optimizing the cellular component that is combined with biomaterials, for improved tissue regeneration.
Mavinga M, Palmier M, Rémy M, Jeannière C, Lenoir S, Rey S, Saint-Marc M, Alonso F, Génot E, Thébaud N, Chevret E, Mournetas V, Rousseau B, Boiziau C, Boeuf H.   +14 more
europepmc   +3 more sources

Stem cells from tooth apical papilla modulate fibromyalgia-like changes in mice

Brain Research Bulletin
Background: The treatment of fibromyalgia remains a current challenge. While the analgesic effects of mesenchymal stem cells have been the subject of previous research, their potential in managing fibromyalgia symptoms needs further investigation.
Ana P.A. Dagnino, Gabriel Rübensam, Jefferson B. Silva, Maria M. Campos   +3 more
doaj   +3 more sources

Functional sensory neurons derived from human stem cells from apical papilla

Indian Journal of Dental Research
Objectives: This study aimed to investigate the sensory maturation–enhancing effects of co-culturing human stem cells from apical papilla (hSCAPs)-derived neural stem cells (NSCs) with chick embryonic dorsal root ganglia (DRG) under three-dimensional (3D)
Pukit Limyothin, Thanawit Juntamongkon, Phubase Chadaratthiti, Tarinee Chodchavanchai, Amarin Thongsuk, Peeratchai Seemaung, Nisarat Ruangsawasdi, Tatcha Balit, Charoensri Thonabulsombat, Anupong T. Songsaad   +9 more
doaj   +2 more sources

Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells [PDF]

Scientific Reports, 2019
AbstractAfter spinal cord injury (SCI) chronic inflammation hampers regeneration. Influencing the local microenvironment after SCI may provide a strategy to modulate inflammation and the immune response. The objectives of this work were to determine whether bone or spinal cord derived ECM hydrogels can deliver human mesenchymal stem cells from the ...
Natalija Tatic, Felicity R. A. J. Rose, Anne des Rieux, Lisa J. White   +3 more
openaire   +6 more sources

EVALUATION OF THE ADHESION AND MORPHOLOGY OF STEM CELLS FROM APICAL PAPILLA IN DIRECT CONTACT WITH MTA AND BIODENTINE [PDF]

Journal of IMAB, 2022
Purpose: To investigate the use of tricalcium silicate cement Biodentine as an alternative to MTA in regenerative endodontic procedures by assessing the morphology and adhesion of stem cells from apical papilla in direct contact with these materials ...
Krasimir Hristov, Nikolay Ishkitiev, Marina Miteva, Nataliya Gateva   +3 more
doaj   +1 more source

[Inhibition of autophagy suppresses osteogenic differentiation of stem cells from apical papilla]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2019
To investigate the effects of autophagy on osteogenic differentiation of stem cells from the apical papilla (SCAPs) in the presence of tumor necrosis factor-α (TNF-α) stimulation in vitro.SCAPs treated with TNF-α (0, 5, and 10 ng/mL) with or without 5 mmol/L 3-MA were examined for the expression of autophagy marker LC3-Ⅱ using Western blotting.
Huang Y, Xiong H, Chen K, Zhu X, Yin X, Liang Y, Luo W, Lei Q.   +7 more
europepmc   +3 more sources

Formation of Three-Dimensional Spheres Enhances the Neurogenic Potential of Stem Cells from Apical Papilla. [PDF]

Bioengineering (Basel), 2022
Cell-based neural regeneration is challenging due to the difficulty in obtaining sufficient neural stem cells with clinical applicability. Stem cells from apical papilla (SCAPs) originating from embryonic neural crests with high neurogenic potential ...
Basabrain MS, Zhong J, Luo H, Liu J, Yi B, Zaeneldin A, Koh J, Zou T, Zhang C.   +8 more
europepmc   +2 more sources