Results 11 to 20 of about 51,719,422 (207)

Conversion of stem cells from apical papilla into endothelial cells by small molecules and growth factors [PDF]

Stem Cell Research & Therapy, 2021
Abstract Objectives Recently, a new strategy has been developed to directly reprogram one cell type towards another targeted cell type using small molecule compounds. Human fibroblasts have been chemically reprogrammed into neuronal cells, Schwann cells and cardiomyocyte-like cells by different small molecule ...
Baicheng Yi, Tian Ding, Shan Jiang, Ting Gong, Hitesh Chopra, Ou Sha, Waruna Lakmal Dissanayaka, Shaohua Ge, Chengfei Zhang   +8 more
europepmc   +6 more sources

The Effect of Liquid-Phase Exfoliated Graphene Film on Neurodifferentiation of Stem Cells from Apical Papilla [PDF]

Nanomaterials, 2022
Background: Dental stem cells, which originate from the neural crest, due to their easy accessibility might be good candidates in neuro-regenerative procedures, along with graphene-based nanomaterials shown to promote neurogenesis in vitro.
Jelena Simonovic, Bosko Toljic, Milos Lazarevic, Maja Milosevic Markovic, Mina Peric, Jasna Vujin, Radmila Panajotovic, Jelena Milasin   +7 more
doaj   +2 more sources

The Journey of SCAPs (Stem Cells from Apical Papilla), from Their Native Tissue to Grafting: Impact of Oxygen Concentration. [PDF]

Cells, 2022
Tissue engineering strategies aim at characterizing and at optimizing the cellular component that is combined with biomaterials, for improved tissue regeneration.
Mavinga M, Palmier M, Rémy M, Jeannière C, Lenoir S, Rey S, Saint-Marc M, Alonso F, Génot E, Thébaud N, Chevret E, Mournetas V, Rousseau B, Boiziau C, Boeuf H.   +14 more
europepmc   +2 more sources

The Role of MicroRNA in the Behaviour of Periodontal Ligament Stem Cells and Stem Cells from the Apical Papilla: A Systematic Review

Stem Cell Reviews and Reports
Abstract Aim This systematic review aimed to synthesize current evidence on the regulatory role of microRNAs (miRNAs) in the viability, proliferation, osteo-odontogenic differentiation potential and/or inflammation of periodontal ligament stem cells (PDLSCs) and stem cells from the apical ...
José Luis, Sanz, Leopoldo, Forner, Sergio, López-García, Francisco Javier, Rodríguez-Lozano, João Miguel, Santos, Sofía, Folguera, Concha, López-Ginés, Daniel, Monleón   +7 more
core   +11 more sources

Effect of Long-Term Cryopreservation on the Stemness of Stem Cells of Apical Papilla

International Journal of Dentistry, 2022
Stem cells of apical papilla (SCAPs) are considered a subpopulation of dental stem cells with unique properties. They originate from a developing tissue, the apical papilla of developing teeth, a characteristic that enhances their stemness.
Anna Digka, Eleni Gounari, Kokkona Kouzi-Koliakou, Kleoniki Lyroudia   +3 more
doaj   +2 more sources

Potential of resveratrol in enrichment of neural progenitor-like cell induction of human stem cells from apical papilla [PDF]

Stem Cell Research & Therapy, 2020
Introduction Stem cell transplantation of exogenous neural progenitor cells (NPCs) derived from mesenchymal stem cells (MSCs) has emerged as a promising approach for neurodegenerative disease.
Anupong Songsaad, Thanasup Gonmanee, Nisarat Ruangsawasdi, Chareerut Phruksaniyom, Charoensri Thonabulsombat   +4 more
doaj   +2 more sources

Hypoxic stem cells from apical papilla-derived exosomes enhance dental pulp stem cells migration and differentiation via mitochondrial activation [PDF]

Journal of Dental Sciences
Background/purpose: Stem cells from apical papilla (SCAPs) and dental pulp stem cells (DPSCs) play critical roles in dental tissue regeneration. Although intercellular communication through exosomes is known to influence stem cell regulation, the effects
Deyan Yuan, Rui Tao, Bi Yin, Meng Gu
doaj   +2 more sources

DLX5 and HOXC8 enhance the chondrogenic differentiation potential of stem cells from apical papilla via LINC01013 [PDF]

Stem Cell Research & Therapy, 2020
Background Mesenchymal stem cell (MSC)-based cartilage tissue regeneration is a treatment with great potential. How to enhance the MSC chondrogenic differentiation is a key issue involved in cartilage formation.
Haoqing Yang, Yangyang Cao, Jianpeng Zhang, Yuncun Liang, Xiaomin Su, Chen Zhang, Huina Liu, Xiao Han, Lihua Ge, Zhipeng Fan   +9 more
doaj   +2 more sources

Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction [PDF]

Journal of Applied Oral Science, 2023
Objectives The endogenous repairing based on the activation of neural stem cells (NSCs) is impaired by neurodegenerative diseases. The present study aims to characterize human stem cells from the apical papilla (hSCAPs) with features of mesenchymal stem
Anupong Thongklam SONGSAAD, Sarut THAIRAT, Peeratchai SEEMAUNG, Amarin THONGSUK, Tatcha BALIT, Nisarat RUANGSAWASDI, Chareerut PHRUKSANIYOM, Thanasup GONMANEE, Kenneth L. WHITE, Charoensri THONABULSOMBAT   +9 more
doaj   +2 more sources

Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization [PDF]

Stem Cell Research & Therapy, 2021
Background Reconstruction of complex critical-size defects (CSD) in the craniofacial region is a major challenge, and soft tissue regeneration is crucial in determining the therapeutic outcomes of craniofacial CSD.
Yao Liu, Xueying Zhuang, Si Yu, Ning Yang, Jianhong Zeng, Xuemei Liu, Xu Chen   +6 more
doaj   +2 more sources