Results 11 to 20 of about 4,536 (207)

Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla [PDF]

BMC Oral Health
Background Simvastatin modulates numerous stem cell functions, including stemness maintenance and differentiation. The present study aimed to explore the effect of simvastatin on the osteogenic differentiation of Stem Cells isolated from Apical Papilla ...
Paak Rewthamrongsris, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Prim Janjarussakul, Chatvadee Kornsuthisopon, Lakshman Samaranayake, Thanaphum Osathanon   +6 more
doaj   +4 more sources

Effect of Long-Term Cryopreservation on the Stemness of Stem Cells of Apical Papilla [PDF]

International Journal of Dentistry, 2022
Stem cells of apical papilla (SCAPs) are considered a subpopulation of dental stem cells with unique properties. They originate from a developing tissue, the apical papilla of developing teeth, a characteristic that enhances their stemness.
Anna Digka, Eleni Gounari, Kokkona Kouzi-Koliakou, Kleoniki Lyroudia   +3 more
doaj   +2 more sources

Effects of ethylenediaminetetraacetic acid on stem cells from the apical papilla: In vitro study [PDF]

Journal of Dental Sciences, 2023
Ethylenediaminetetraacetic acid (EDTA) is used as an irrigant in regenerative endodontic treatment. The present study aimed to investigate the effects of EDTA on stem cells from apical papilla (SCAPs) in vitro.Human SCAPs were isolated and characterised. The cells were treated with media supplemented with EDTA at concentrations ranging from 1.25% to 17%
Suphalak Phothichailert, Benya Sangwisutsai, Dhitinant Rattanakosol, Nutcha Teerapongpaibul, Sirawut Hiran-us, Nunthawan Nowwarote, Thanaphum Osathanon   +6 more
core   +7 more sources

Molecular Biological Comparison of Dental Pulp- and Apical Papilla-Derived Stem Cells [PDF]

International Journal of Molecular Sciences, 2022
Both the dental pulp and the apical papilla represent a promising source of mesenchymal stem cells for regenerative endodontic protocols. The aim of this study was to outline molecular biological conformities and differences between dental pulp stem ...
Woelflick, Melanie, Moehle, Christoph, Buchalla, Wolfgang, Smeda, Martyna, Beate Lenhardt, Melanie Woelflick, Christoph Moehle, Martyna Smeda, Galler, Kerstin M., Andreas Rosendahl, Rosendahl, Andreas, Matthias Widbiller, Lenhardt, Beate, Widbiller, Matthias, Kerstin M. Galler, Wolfgang Buchalla   +15 more
core   +3 more sources

Establishing and characterizing human stem cells from the apical papilla immortalized by hTERT gene transfer [PDF]

Frontiers in Cell and Developmental Biology, 2023
Stem cells from the apical papilla (SCAPs) are promising candidates for regenerative endodontic treatment and tissue regeneration in general. However, harvesting enough cells from the limited apical papilla tissue is difficult, and the cells lose their ...
Qianyu Cheng, Qianyu Cheng, Qianyu Cheng, Qianyu Cheng, Chang Liu, Chang Liu, Chang Liu, Chang Liu, Qiuman Chen, Wenping Luo, Tong-Chuan He, Deqin Yang, Deqin Yang, Deqin Yang, Deqin Yang   +14 more
doaj   +3 more sources

Characterization of neural stem cells derived from human stem cells from the apical papilla undergoing three-dimensional neurosphere induction [PDF]

Journal of Applied Oral Science, 2023
Objectives The endogenous repairing based on the activation of neural stem cells (NSCs) is impaired by neurodegenerative diseases. The present study aims to characterize human stem cells from the apical papilla (hSCAPs) with features of mesenchymal stem
Anupong Thongklam SONGSAAD, Sarut THAIRAT, Peeratchai SEEMAUNG, Amarin THONGSUK, Tatcha BALIT, Nisarat RUANGSAWASDI, Chareerut PHRUKSANIYOM, Thanasup GONMANEE, Kenneth L. WHITE, Charoensri THONABULSOMBAT   +9 more
doaj   +3 more sources

MiR-199a-5P promotes osteogenic differentiation of human stem cells from apical papilla via targeting IFIT2 in apical periodontitis [PDF]

Frontiers in Immunology, 2023
IntroductionPeriapical alveolar bone loss is the common consequence of apical periodontitis (AP) caused by persistent local inflammation around the apical area.
Jing Hu, Jing Hu, Xia Huang, Liwen Zheng, Liwen Zheng, Yuxin Zhang, Yuxin Zhang, Huan Zeng, Huan Zeng, Li Nie, Xiaoxiao Pang, Xiaoxiao Pang, Hongmei Zhang, Hongmei Zhang   +13 more
doaj   +2 more sources

Basic Fibroblast Growth Factor Enhances Stemness of Human Stem Cells from the Apical Papilla [PDF]

Journal of Endodontics, 2012
Stem cells from the apical papilla (SCAP) are a type of mesenchymal stem cells found in the developing tissue, apical papilla, of immature permanent teeth. Studies have shown that SCAP are likely to be a source of primary odontoblasts that are responsible for the formation of root dentin.
Jiayuan, Wu, George T-J, Huang, Wenxi, He, Ping, Wang, Zhongchun, Tong, Qian, Jia, Liping, Dong, Zhongying, Niu, Longxing, Ni   +8 more
openaire   +4 more sources

Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization [PDF]

Stem Cell Research & Therapy, 2021
Background Reconstruction of complex critical-size defects (CSD) in the craniofacial region is a major challenge, and soft tissue regeneration is crucial in determining the therapeutic outcomes of craniofacial CSD.
Yao Liu, Xueying Zhuang, Si Yu, Ning Yang, Jianhong Zeng, Xuemei Liu, Xu Chen   +6 more
doaj   +2 more sources

A pilot study on biological characteristics of human CD24(+) stem cells from the apical papilla

Journal of Dental Sciences, 2022
Background/purpose: CD24 is a specific cell surface marker for undifferentiated dental stem cells from apical papilla (SCAPs) seen only during root development, before the tooth emerges through gum.
Jing Liang, Ya-Jin Zhao, Jun-Qing Li, Lan Lan, Wen-Jing Tao, Jia-Yuan Wu   +5 more
doaj   +3 more sources