Results 11 to 20 of about 8,372 (230)

MiR-199a-5P promotes osteogenic differentiation of human stem cells from apical papilla via targeting IFIT2 in apical periodontitis [PDF]

Frontiers in Immunology, 2023
IntroductionPeriapical alveolar bone loss is the common consequence of apical periodontitis (AP) caused by persistent local inflammation around the apical area.
Jing Hu, Jing Hu, Xia Huang, Liwen Zheng, Liwen Zheng, Yuxin Zhang, Yuxin Zhang, Huan Zeng, Huan Zeng, Li Nie, Xiaoxiao Pang, Xiaoxiao Pang, Hongmei Zhang, Hongmei Zhang   +13 more
doaj   +2 more sources

Basic Fibroblast Growth Factor Enhances Stemness of Human Stem Cells from the Apical Papilla [PDF]

Journal of Endodontics, 2012
Stem cells from the apical papilla (SCAP) are a type of mesenchymal stem cells found in the developing tissue, apical papilla, of immature permanent teeth. Studies have shown that SCAP are likely to be a source of primary odontoblasts that are responsible for the formation of root dentin.
Jiayuan, Wu, George T-J, Huang, Wenxi, He, Ping, Wang, Zhongchun, Tong, Qian, Jia, Liping, Dong, Zhongying, Niu, Longxing, Ni   +8 more
openaire   +4 more sources

INFLUENCE OF STORAGE MEDIA ON THE VITALITY OF STEM CELLS FROM APICAL PAPILLA [PDF]

Journal of IMAB, 2018
Purpose: Immediate replantation is the treatment of choice for avulsed permanent teeth. Transportation of avulsed teeth to the dentist office requires storage in suitable media, thus keeping periodontal and periapical tissues viable.
Krasimir Hristov, Natalia Gateva, Pavel Stanimirov, Nikolay Ishkitiev, Rozaliya Tsikandelova   +4 more
doaj   +3 more sources

Simvastatin modulates osteogenic differentiation in Stem Cells isolated from Apical Papilla

BMC Oral Health
Background Simvastatin modulates numerous stem cell functions, including stemness maintenance and differentiation. The present study aimed to explore the effect of simvastatin on the osteogenic differentiation of Stem Cells isolated from Apical Papilla ...
Paak Rewthamrongsris, Suphalak Phothichailert, Uraiwan Chokechanachaisakul, Prim Janjarussakul, Chatvadee Kornsuthisopon, Lakshman Samaranayake, Thanaphum Osathanon   +6 more
doaj   +3 more sources

Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization [PDF]

Stem Cell Research & Therapy, 2021
Background Reconstruction of complex critical-size defects (CSD) in the craniofacial region is a major challenge, and soft tissue regeneration is crucial in determining the therapeutic outcomes of craniofacial CSD.
Yao Liu, Xueying Zhuang, Si Yu, Ning Yang, Jianhong Zeng, Xuemei Liu, Xu Chen   +6 more
doaj   +2 more sources

Electric field promoted odontogenic differentiation of stem cells from apical papilla by remodelling cytoskeleton. [PDF]

Int Endod J
AbstractAimThis study examined the impact of direct current electric fields (DCEFs) on the biological properties of stem cells derived from the apical papilla (SCAP) and further elucidated the underlying mechanisms involved in odontogenic differentiation induced by DCEFs stimulation.MethodologyThe measurement of endogenous currents in wounded dentine ...
Li X, Zhao S, Liu Y, Gu Y, Qiu L, Chen X, Sloan AJ, Song B.   +7 more
europepmc   +3 more sources

Stem cells from tooth apical papilla modulate fibromyalgia-like changes in mice

Brain Research Bulletin
Background: The treatment of fibromyalgia remains a current challenge. While the analgesic effects of mesenchymal stem cells have been the subject of previous research, their potential in managing fibromyalgia symptoms needs further investigation.
Ana P.A. Dagnino, Gabriel Rübensam, Jefferson B. Silva, Maria M. Campos   +3 more
doaj   +3 more sources

[Inhibition of autophagy suppresses osteogenic differentiation of stem cells from apical papilla]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao, 2019
To investigate the effects of autophagy on osteogenic differentiation of stem cells from the apical papilla (SCAPs) in the presence of tumor necrosis factor-α (TNF-α) stimulation in vitro.SCAPs treated with TNF-α (0, 5, and 10 ng/mL) with or without 5 mmol/L 3-MA were examined for the expression of autophagy marker LC3-Ⅱ using Western blotting.
Huang Y, Xiong H, Chen K, Zhu X, Yin X, Liang Y, Luo W, Lei Q.   +7 more
europepmc   +3 more sources

Influence of Citric Acid on the Vitality of Stem Cells from Apical Papilla

Acta Medica Bulgarica, 2018
The endodontic treatment of immature permanent teeth with necrotic pulp is a serious clinical challenge. The chemical agents, used in regenerative procedures, should be selected not only based on their bactericidal/bacteriostatic properties, but also on ...
Hristov Kr., Gateva N., Stanimirov P., Ishkitiev N., Tsikandelova R., Mihaylova Z.   +5 more
doaj   +2 more sources

EVALUATION OF THE ADHESION AND MORPHOLOGY OF STEM CELLS FROM APICAL PAPILLA IN DIRECT CONTACT WITH MTA AND BIODENTINE [PDF]

Journal of IMAB, 2022
Purpose: To investigate the use of tricalcium silicate cement Biodentine as an alternative to MTA in regenerative endodontic procedures by assessing the morphology and adhesion of stem cells from apical papilla in direct contact with these materials ...
Krasimir Hristov, Nikolay Ishkitiev, Marina Miteva, Nataliya Gateva   +3 more
doaj   +1 more source