Osteo/odontogenic differentiation analysis of dental stem cells from tooth germ, apical papilla, and dental follicle [PDF]
Aim: Different tissues of dental origin are used for isolation of stem cells that can be differentiated towards osteogenic or odontogenic lineages, including dental follicle and apical papilla.
Kose, Gamze Torun +7 more
core +1 more source
Neural Regenerative Potential of Stem Cells Derived from the Tooth Apical Papilla [PDF]
The regenerative effects of stem cells derived from dental tissues have been previously investigated. This study assessed the potential of human tooth stem cells from apical papilla (SCAP) on nerve regeneration. The SCAP collected from nine individuals were characterized and polarized by exposure to interferon-γ (IFN-γ).
Ana Paula Aquistapase, Dagnino +8 more
openaire +2 more sources
Characterization of human apical papilla-derived stem cells [PDF]
Dental tissues represent an alternative and promising source of post-natal Mesenchymal stem cells (MSCs) for tissue engineering. Furthermore, dental stem cells from apical papilla (SCAPs) cells can be obtained from the wisdom tooth which is unnecessary ...
Inchingolo, F. +11 more
core +1 more source
Mesenchymal stem cell-mediated functional tooth regeneration in swine. [PDF]
Mesenchymal stem cell-mediated tissue regeneration is a promising approach for regenerative medicine for a wide range of applications. Here we report a new population of stem cells isolated from the root apical papilla of human teeth (SCAP, stem cells ...
Wataru Sonoyama +10 more
doaj +1 more source
Stem Cells from the Apical Papilla: A Promising Source for Stem Cell-Based Therapy
Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages. Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can be used as an alternative to ...
Jun Kang +4 more
openaire +3 more sources
Isolation and Culture of Human Stem Cells from Apical Papilla under Low Oxygen Concentration Highlight Original Properties. [PDF]
International audienceStem cells isolated from the apical papilla of wisdom teeth (SCAPs) are an attractive model for tissue repair due to their availability, high proliferation rate and potential to differentiate in vitro towards mesodermal and ...
Rémy M +8 more
europepmc +3 more sources
Objective: Indirect Jagged1 immobilization efficiently activates canonical Notch signaling in human dental pulp stem cells (hDPSCs). This study aimed to investigate the characteristics of the Jagged1-treated hDPSC-derived decellularized extracellular ...
Suphalak Phothichailert +9 more
doaj +1 more source
Effect of Biodentine Coated with Emdogain on Proliferation and Differentiation of Stem Cells from the Apical Papilla [PDF]
Abstract Background: This study assessed the effect of Biodentine coated with Emdogain (Biodentine/Emdogain) on proliferation and differentiation of stem cells from the apical papilla (SCAP). Methods and Results: In this in vitro, experimental study, SCAP were isolated from two immature impacted third molars and cultured.
Hamed Karkehabadi +3 more
openaire +2 more sources
Stem Cells From the Apical Papilla (SCAP) as a Tool for Endogenous Tissue Regeneration [PDF]
Stem cells extracted from developing tissues possibly exhibit not only unique but also superior traits against their developed counterparts. Indeed, stem cells from the apical papilla (SCAP); a unique group of dental stem cells related to developing roots have been shown to be a promising tool for regenerative endodontic procedures and regeneration in ...
Ola A. Nada +3 more
openaire +3 more sources
Biomaterials and Scaffold Design Strategies for Regenerative Endodontic Therapy
Challenges with traditional endodontic treatment for immature permanent teeth exhibiting pulp necrosis have prompted interest in tissue engineering approaches to regenerate the pulp-dentin complex and allow root development to continue.
Gavin Raddall +3 more
doaj +1 more source

