International Endodontic Journal, 2023 AbstractAimTo establish and fully characterize a new cell line from human stem cells of the apical papilla (SCAPs) through immortalization with an SV40 large T antigen.MethodologyHuman SCAPs were isolated and transfected with an SV40 large T antigen and treated with puromycin to select the infected population.
Diana Sanz‐Serrano +3 more
openaire +3 more sources
Journal of Tissue Engineering, 2022 Apical periodontitis (AP) causes arrest of tooth root development, which is associated with impaired odontoblastic differentiation of stem cells from apical papilla (SCAPs), but the underlying mechanism remains unclear.
Shengyan Yang +8 more
doaj +1 more source
Mechanical plaque removal in step‐1 of care
Periodontology 2000, EarlyView., 2023 Abstract Maintaining a regular oral hygiene routine is essential for taking care of our mouths, ensuring healthy teeth, and achieving fresh breath. Patient education on oral hygiene is an important component of their overall treatment. Firstly, patients should be informed about the direct connection between bacteria in dental plaque and oral diseases ...
G. A. (Fridus) Van der Weijden +1 more
wiley +1 more source
Characterization of Apical Papilla and its Residing Stem Cells from Human Immature Permanent Teeth –A Pilot Study [PDF]
, 2008 Mesenchymal stem cells (MSCs) have been isolated from the pulp tissue of permanent teeth (dental pulp stem cells or DPSCs) and deciduous teeth (stem cells from human exfoliated deciduous teeth or SHED).
Tuan, Rocky S. +6 more
core +2 more sources
Immunomodulatory effects of apical papilla cells on periodontal ligament fibroblasts stimulated with Escherichia coli lipopolysaccharide: an in vitro study [PDF]
Journal of Applied Oral ScienceThe role of human Stem Cells from the Apical Papilla (SCAP) in tissue regeneration has been described, but their impact on modulating the apical inflammatory process by other surrounding cell populations, such as periodontal ligament fibroblasts (PLFs ...
Alexandre Guimarães dos SANTOS +4 more
doaj +1 more source
Evaluation of the Cytotoxicity of Two Types of Triple Antibiotic Paste on Human Permanent Dental Apical Papilla Stem Cells: an in vitro Study [PDF]
Journal of Dentistry, 2022 Statement of the Problem: The use of a new antimicrobial combination in the regenerative endodontic treatment of immature teeth pulp necrosis is a well-known method.
Rezvan Rafatjou +4 more
doaj +1 more source
Lineage differentiation of mesenchymal stem cells from dental pulp, apical papilla, and periodontal ligament [PDF]
, 2012 Recently, a variety of mesenchymal stem cells (MSCs), including dental pulp stem cells, stem cells from human exfoliated deciduous teeth, stem cells from apical papilla, periodontal ligament stem cells, and mesenchymal stem cells derived from human ...
Stan Gronthos +7 more
core +1 more source
Triiodothyronine participates in odontoblast differentiation of apical papilla stem cells through regulation of ERK and p38MAPK signaling pathways [PDF]
, 2022 Purpose: To investigate the effect of triiodothyronine (T3) in odontoblast differentiation of apical papilla stem cells, and the mechanism of action involved.
Yang, Haibing, He, Lei, Xu, Jiali
core +2 more sources
Journal of Clinical and Experimental Dentistry, 2021 Dental Mesenchymal stem cells has prompted great for cell-based therapeutics. But no one knows for sure what the true potential of these cells, since most of the studies were done in isolation, using as source, different donors or different cell processing conditions.An enriched population of cells positive for CD146, STRO-1, and CD90 was isolated of ...
Rezende, Karla Mayra P. C. +6 more
openaire +3 more sources
Effect of taxifolin and epigallocatechin-3-gallate on biomineralization potential of stem cells from dental apical papilla [PDF]
, 2022 Objective: Considering the variety of pharmacological activities and the potential to mediate biomineralization, the flavonoids taxifolin and epigallocatechin-3-gallate (EGCG) could be explored as biomolecules in scaffolds for regenerative endodontic ...
Bortolatto, Janaina +4 more
core +1 more source