Results 41 to 50 of about 4,117 (183)

Basic Fibroblast Growth Factor Enhances Stemness of Human Stem Cells from the Apical Papilla [PDF]

Journal of Endodontics, 2012
Stem cells from the apical papilla (SCAP) are a type of mesenchymal stem cells found in the developing tissue, apical papilla, of immature permanent teeth. Studies have shown that SCAP are likely to be a source of primary odontoblasts that are responsible for the formation of root dentin.
Jiayuan, Wu, George T-J, Huang, Wenxi, He, Ping, Wang, Zhongchun, Tong, Qian, Jia, Liping, Dong, Zhongying, Niu, Longxing, Ni   +8 more
openaire   +2 more sources

Dental Stem Cells SV40, a new cell line developed in vitro from human stem cells of the apical papilla

International Endodontic Journal, 2023
AbstractAimTo establish and fully characterize a new cell line from human stem cells of the apical papilla (SCAPs) through immortalization with an SV40 large T antigen.MethodologyHuman SCAPs were isolated and transfected with an SV40 large T antigen and treated with puromycin to select the infected population.
Diana Sanz‐Serrano, Cristina Sánchez‐de‐Diego, Montse Mercade, Francesc Ventura   +3 more
openaire   +3 more sources

Extracellular vesicles delivering nuclear factor I/C for hard tissue engineering: Treatment of apical periodontitis and dentin regeneration

Journal of Tissue Engineering, 2022
Apical periodontitis (AP) causes arrest of tooth root development, which is associated with impaired odontoblastic differentiation of stem cells from apical papilla (SCAPs), but the underlying mechanism remains unclear.
Shengyan Yang, Qing Liu, Shijing Chen, Fuping Zhang, Yaoyin Li, Wenguo Fan, Lijia Mai, Hongwen He, Fang Huang   +8 more
doaj   +1 more source

Mechanical plaque removal in step‐1 of care

Periodontology 2000, EarlyView., 2023
Abstract Maintaining a regular oral hygiene routine is essential for taking care of our mouths, ensuring healthy teeth, and achieving fresh breath. Patient education on oral hygiene is an important component of their overall treatment. Firstly, patients should be informed about the direct connection between bacteria in dental plaque and oral diseases ...
G. A. (Fridus) Van der Weijden, Cor van Loveren   +1 more
wiley   +1 more source

Immunomodulatory effects of apical papilla cells on periodontal ligament fibroblasts stimulated with Escherichia coli lipopolysaccharide: an in vitro study [PDF]

Journal of Applied Oral Science
The role of human Stem Cells from the Apical Papilla (SCAP) in tissue regeneration has been described, but their impact on modulating the apical inflammatory process by other surrounding cell populations, such as periodontal ligament fibroblasts (PLFs ...
Alexandre Guimarães dos SANTOS, Karollyne Santos SPIGARIOL, Letícia Martins SANTOS, Marinella HOLZHAUSEN, Carla Renata SIPERT   +4 more
doaj   +1 more source

Evaluation of the Cytotoxicity of Two Types of Triple Antibiotic Paste on Human Permanent Dental Apical Papilla Stem Cells: an in vitro Study [PDF]

Journal of Dentistry, 2022
Statement of the Problem: The use of a new antimicrobial combination in the regenerative endodontic treatment of immature teeth pulp necrosis is a well-known method.
Rezvan Rafatjou , Arghavan Kamali Sabeti , Bahar Ahmadi , Sara Soleimani Asl , Maryam Farhadian   +4 more
doaj   +1 more source

Stem cells from human dental pulp and apical papilla: Morphological and synchrotron radiation analysis

Journal of Clinical and Experimental Dentistry, 2021
Dental Mesenchymal stem cells has prompted great for cell-based therapeutics. But no one knows for sure what the true potential of these cells, since most of the studies were done in isolation, using as source, different donors or different cell processing conditions.An enriched population of cells positive for CD146, STRO-1, and CD90 was isolated of ...
Rezende, Karla Mayra P. C., Bönecker, Marcelo, Corrêa, Luciana, Perez, Carlos-Alberto, Brito, Giancarlo-Espósito-de Souza, Berti, Gabriela-Oliveira, Pobocik, Andrea-Mantesso   +6 more
openaire   +3 more sources

Molecular insight into odontogenesis in hyperglycemic environment: A systematic review

Journal of Pharmacy and Bioallied Sciences, 2020
Diabetes mellitus is an endocrinal disorder affecting worldwide and the disease incidence is rising alarmingly high. The effects of diabetes on tooth development are explored by limited studies and their molecular insights are very rarely studied.
Andamuthu Yamunadevi, Ramani Pratibha, Muthusamy Rajmohan, Nalliappan Ganapathy, Jeyachandran Porkodisudha, Dhanasing Pavithrah, Sengottaiyan Mahendraperumal   +6 more
doaj   +1 more source

Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study

Biological Procedures Online, 2023
Background Periodontal regeneration, treatment of periodontal-related diseases and improving the function of implants are global therapeutic challenges. The differentiation of human stem cells from apical papilla into cementoblasts may provide a strategy
Morvarid Ebadi, Amirfarhang Miresmaeili, Sarah Rajabi, Shahrokh Shojaei, Sareh Farhadi   +4 more
doaj   +1 more source

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

Advanced Healthcare Materials, EarlyView.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître, Marina Trouillas, Tatiana Vinasco‐Sandoval, Cécile Giordano, Alexandre G. Lellouch, Walid Rachidi, Jean‐Jacques Lataillade, Nicolas O. Fortunel   +7 more
wiley   +1 more source