Results 71 to 80 of about 429,888 (408)

Sparse, Decorrelated Odor Coding in the Mushroom Body Enhances Learned Odor Discrimination

Nature Neuroscience, 2014
Sparse coding may be a general strategy of neural systems for augmenting memory capacity. In Drosophila melanogaster, sparse odor coding by the Kenyon cells of the mushroom body is thought to generate a large number of precisely addressable locations for
Andrew C. Lin, A. Bygrave, Alix de Calignon, Tzumin Lee, G. Miesenböck   +4 more
semanticscholar   +1 more source

Odors, words and objects [PDF]

, 2016
The paper focuses on concepts and words referring to odors and to objects that have an odor. We argue that odors are an interesting object of study since they are evanescent, and since odor words do not refer to concrete and manipulable ...
BORGHI, ANNA MARIA, Cimatti, Felice, Flumini, Andrea, Vittuari, Martina   +3 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Restoring the Spirit through the Redemption of Memory

Religions
Restoration and redemption of the soul are, in biblical terms, essentially life-bringing acts. Yet even the present reality is so frequently a spirit deeply in need of renewal and new life.
Judith Odor
doaj   +1 more source

Olfactory receptor neurons generate multiple response motifs, increasing coding space dimensionality

eLife, 2023
Odorants binding to olfactory receptor neurons (ORNs) trigger bursts of action potentials, providing the brain with its only experience of the olfactory environment.
Brian Kim, Seth Haney, Ana P Milan, Shruti Joshi, Zane Aldworth, Nikolai Rulkov, Alexander T Kim, Maxim Bazhenov, Mark A Stopfer   +8 more
doaj   +1 more source

Predicting odor perceptual similarity from odor structure [PDF]

Flavour, 2013
To understand the brain mechanisms of olfaction we must understand the rules that govern the link between odorant structure and odorant perception. Natural odors are in fact mixtures made of many molecules, and there is currently no method to look at the molecular structure of such odorant-mixtures and predict their smell. In three separate experiments,
Idan Frumin, Kobi Snitz, Adi Yablonka, Noam Sobel, Rehan M. Khan, Tali Weiss   +5 more
openaire   +6 more sources

Testing for odor discrimination and habituation in mice.

Journal of Visualized Experiments, 2015
This video demonstrates a technique to establish the presence of a normally functioning olfactory system in a mouse. The test helps determine whether the mouse can discriminate between non-social odors and social odors, whether the mouse habituates to a ...
E. Arbuckle, Gregory D. Smith, M. C. Gomez, J. Lugo   +3 more
semanticscholar   +1 more source

Contribution of the cyclic nucleotide gated channel subunit, CNG-3, to olfactory plasticity in Caenorhabditis elegans. [PDF]

, 2017
In Caenorhabditis elegans, the AWC neurons are thought to deploy a cGMP signaling cascade in the detection of and response to AWC sensed odors. Prolonged exposure to an AWC sensed odor in the absence of food leads to reversible decreases in the animal's ...
BT Juang, C Peng, CI Bargmann, CM Coburn, CM Coburn, DM O’Halloran, DM O’Halloran, ER Troemel, F Paquet-Durand, H Komatsu, H Komatsu, H Zhong, H Zhong, HA Colbert, HA Colbert, HK Smith, J Bradley, J Zheng, J Zheng, JA Kaye, JF Etchberger, JI Lee, JL Krajewski, KR Kelliher, M Wojtyniak, MC Trudeau, N Blom, ND L’Etoile, O Hobert, PD Wes, PM Jenkins, S Brenner, S Kohl, S Michalakis, SW Cho, SW Cho, TK Kerppola, TY Chen, Y Song, YJ Shyu   +39 more
core   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Chemical Characterization of Human Body Odor Headspace Components

Separations
This study focused on evaluating human body odor volatiles using a chamber approach. Ten participants were asked to sit inside the chamber for 1 h, while using SPME as the extraction technique for vapor sampling.
A. Celeste Medrano, Ariela Cantu, Edgar O. Aviles-Rosa, Nathaniel J. Hall, Michele N. Maughan, Jenna D. Gadberry, Paola A. Prada-Tiedemann   +6 more
doaj   +1 more source