Results 51 to 60 of about 10,413,734 (287)

Left Posterior Orbitofrontal Cortex Is Associated With Odor-Induced Autobiographical Memory: An fMRI Study

Frontiers in Psychology, 2018
Autobiographical odor memory (AM-odor) accompanied by a sense of realism of a specific memory elicits strong emotions. AM-odor differs from memory triggered by other sensory modalities, possibly because olfaction involves a unique sensory process.
Keiko Watanabe, Keiko Watanabe, Yuri Masaoka, Mitsuru Kawamura, Masaki Yoshida, Nobuyoshi Koiwa, Akira Yoshikawa, Satomi Kubota, Satomi Kubota, Masahiro Ida, Kenjiro Ono, Masahiko Izumizaki   +11 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Linkage between increased nociception and olfaction via a SCN9A haplotype [PDF]

, 2013
Background and Aims: Mutations reducing the function of Nav1.7 sodium channels entail diminished pain perception and olfactory acuity, suggesting a link between nociception and olfaction at ion channel level.
Hummel, Thomas, Bruno G Oertel, Lötsch, Jörn, Thomas Hummel, Jörn Lötsch, Doehring, Alexandra, Dirk Heimann, Heimann, Dirk, Alexandra Doehring, Oertel, Bruno Georg   +9 more
core   +2 more sources

Recall of Odorous Objects in Virtual Reality

Multimodal Technologies and Interaction
The aim was to investigate how the congruence of odors and visual objects in virtual reality (VR) affects later memory recall of the objects. Participants (N = 30) interacted with 12 objects in VR. The interaction was varied by odor congruency (i.e., the
Jussi Rantala, Katri Salminen, Poika Isokoski, Ville Nieminen, Markus Karjalainen, Jari Väliaho, Philipp Müller, Anton Kontunen, Pasi Kallio, Veikko Surakka   +9 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Participação do receptor beta-adrenérgico na modulação do comportamento defensivo de ratos expostos ao odor de gato [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Estudos têm demonstrado que o odor do predador é um potente estímulo ansiogênico, fornecendo elementos para a ...
Monte, Fabrício Hoffmann Martins do
core  

Unpleasant Food Odors Modulate the Processing of Facial Expressions: An Event-Related Potential Study

Frontiers in Neuroscience, 2020
In real-life situations, emotional information is often expressed through multiple sensory channels, with cross-talk between channels. Previous research has established that odor environments regulate the recognition of facial expressions.
Danyang Li, Jiafeng Jia, Xiaochun Wang
doaj   +1 more source

Novelty detection in early olfactory processing of the honey bee, Apis mellifera.

PLoS ONE, 2022
Animals are constantly bombarded with stimuli, which presents a fundamental problem of sorting among pervasive uninformative stimuli and novel, possibly meaningful stimuli.
Hong Lei, Seth Haney, Christopher M Jernigan, Xiaojiao Guo, Chelsea N Cook, Maxim Bazhenov, Brian H Smith   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Motor Cortex Response to Pleasant Odor Perception and Imagery: The Differential Role of Personality Dimensions and Imagery Ability

Frontiers in Human Neuroscience, 2022
BackgroundNeuroimaging studies have shown a complex pattern of brain activation during perception of a pleasant odor and during its olfactory imagery. To date, little is known regarding changes in motor cortex excitability during these tasks.
Carmenrita Infortuna, Francesca Gualano, Francesca Gualano, David Freedberg, Sapan P. Patel, Asad M. Sheikh, Maria Rosaria Anna Muscatello, Antonio Bruno, Carmela Mento, Eileen Chusid, Zhiyong Han, Florian P. Thomas, Fortunato Battaglia, Fortunato Battaglia   +13 more
doaj   +1 more source