Results 91 to 100 of about 18,427 (225)

Olfactory receptor accessory proteins play crucial roles in receptor function and gene choice [PDF]

, 2017
Each of the olfactory sensory neurons (OSNs) chooses to express a single G protein-coupled olfactory receptor (OR) from a pool of hundreds. Here, we show the receptor transporting protein (RTP) family members play a dual role in both normal OR ...
Abdus-Saboor, Aisenberg, Armelin-Correa, Aungst, Barnea, Bray, Bronson, Brunet, Buck, Carter, Chang, Chess, Col, Cowan, Dalton, Dey, Feingold, Feinstein, Feinstein, Feldmesser, Ferreira, Flegel, Gimelbrant, Gire, Godin, Griffin, Hague, Hanchate, Hayar, Ibarra-Soria, Jamet, Jia, Jiang, Kanageswaran, Kang, Kang, Khan, Kilinc, Knight, Kouadjo, Laird, Lewcock, Li, Li, Lu, Lyons, Lyons, Madisen, Magklara, Malnic, Markenscoff-Papadimitriou, Meiri, Miyamichi, Mombaerts, Nakashima, Neuhaus, Nguyen, Niimura, Omura, Pacifico, Pluznick, Pluznick, Ressler, Ressler, Robinson, Rogers, Roppolo, Saito, Salahpour, Saraiva, Serizawa, Serizawa, Shykind, Tan, Treloar, Vassar, Vassar, Verhaagen, Wang, Wang, Wei, Wong, Wu, Zhou, Zhuang, Zhuang   +85 more
core   +2 more sources

The porcine odorant-binding protein as molecular probe for benzene detection. [PDF]

PLoS ONE, 2018
In recent years, air pollution has been a subject of great scientific and public interests for the strong impact on human health. Air pollution is due to the presence in the atmosphere of polluting substances, such as carbon monoxide, sulfur and nitrogen
Alessandro Capo, Angela Pennacchio, Antonio Varriale, Sabato D'Auria, Maria Staiano   +4 more
doaj   +1 more source

Ca2+-sensors and ROS-GC: interlocked sensory transduction elements: a review [PDF]

, 2012
From its initial discovery that ROS-GC membrane guanylate cyclase is a mono-modal Ca2+-transduction system linked exclusively with the phototransduction machinery to the successive finding that it embodies a remarkable bimodal Ca2+signaling device, its ...
Rameshwar K. Sharma, Teresa Duda
core   +1 more source

Diversity of Odorant-binding Proteins and Chemosensory Proteins in Insects [PDF]

Chemical Senses, 2005
Odour and pheromone perception occurs through a complex series of events, many aspects of which have been elucidated in the most recent years. The discovery of membrane-bound olfactory receptors, both in vertebrates and in insects, and their functional expression in heterologous systems have shown that they can be directly activated by odorant and ...
PELOSI, PAOLO, Calvello M, Ban LP
openaire   +3 more sources

Molecular bases of insect odorant receptor function: specificity and evolution

Biological Reviews, Volume 101, Issue 2, Page 1036-1049, April 2026.
ABSTRACT Insect odorant receptors (ORs) are a class of chemoreceptors that insects use to detect volatile cues in their environment. In recent years, major advances in the field of structural biology have made it possible to obtain the first structures of insect ORs.
Zibo Li, Abhinob Baruah, Sridevi Bhamidipati, Nicolas Montagné, Emmanuelle Jacquin‐Joly, Camille Meslin   +5 more
wiley   +1 more source

Identification of the Plasticity-Relevant Fucose-α(1−2)-Galactose Proteome from the Mouse Olfactory Bulb [PDF]

, 2009
Fucose-α(1−2)-galactose [Fucα(1−2)Gal] sugars have been implicated in the molecular mechanisms that underlie neuronal development, learning, and memory. However, an understanding of their precise roles has been hampered by a lack of information regarding
Domino, Steven E., Ficarro, Scott B., Hsieh-Wilson, Linda C., Krishnamurthy, Chithra, Murrey, Heather E., Peters, Eric C.   +5 more
core   +4 more sources

How Different Traditional and Modern Coffee Brewing Methods Affect Its Aroma, Chemistry, Health Effects and Safety Attributes?—A Comprehensive Review to Maximize Coffee Brew Quality

eFood, Volume 7, Issue 2, April 2026.
This review article provides a comprehensive analysis of coffee pre‐brewing techniques, focusing on the methodology and key parameters involved in each coffee brewing process. It also summarizes how different brewing methods affect the coffee metabolome, antioxidant levels, aroma, and physicochemical features.
Enas A. El‐Hawary, Hania A. Guirguis, Nik Muhammad Azhar Nik Daud, Mohd Asraf Zainudin, Ahmed Mediani, Mohamed A. Farag   +5 more
wiley   +1 more source

Purinergic receptor antagonists inhibit odorant-mediated CREB phosphorylation in sustentacular cells of mouse olfactory epithelium [PDF]

, 2011
Background Extracellular nucleotides have long been known to play neuromodulatory roles and to be involved in intercellular signalling. In the olfactory system, ATP is released by olfactory neurons, and exogenous ATP can evoke an increase in ...
Ruth Dooley, Anastasia Mashukova, Bastian Toetter, Hanns Hatt, Eva M Neuhaus   +4 more
core   +2 more sources

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Humidity response depends on the small soluble protein Obp59a in Drosophila

eLife, 2018
Hygrosensation is an essential sensory modality that is used to find sources of moisture. Hygroreception allows animals to avoid desiccation, an existential threat that is increasing with climate change.
Jennifer S Sun, Nikki K Larter, J Sebastian Chahda, Douglas Rioux, Ankita Gumaste, John R Carlson   +5 more
doaj   +1 more source