Results 1 to 10 of about 35,320 (207)

Heterologous investigation of metabotropic and ionotropic odorant receptors in ab3A neurons of Drosophila melanogaster

Frontiers in Molecular Biosciences
In insects, antennal ionotropic receptors (IRs) and odorant receptors (ORs) are among the main sensors of olfactory cues. To functionally characterize the subunits from these receptors, the use of ab3A neurons from transgenic Drosophila melanogaster ...
Johan Henning Pettersson, Alberto Maria Cattaneo, Alberto Maria Cattaneo, Alberto Maria Cattaneo   +3 more
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Group 1 metabotropic glutamate receptor function and its regulation of learning and memory in the aging brain

Frontiers in Pharmacology, 2012
Normal aging is generally characterized by a slow decline of cognitive abilities albeit with marked individual differences. Several animal models have been studied to explore the molecular and cellular mechanisms underlying this phenomenon.
Caroline eMénard, Rémi eQuirion
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Neuroanatomical changes of ionotropic glutamatergic and GABAergic receptor densities in male mice modeling idiopathic and syndromic autism spectrum disorder

Frontiers in Psychiatry, 2023
Autism spectrum disorder (ASD) comprises a wide range of neurodevelopment conditions primarily characterized by impaired social interaction and repetitive behavior, accompanied by a variable degree of neuropsychiatric characteristics.
Leonardo Nardi, Stuti Chhabra, Stuti Chhabra, Petra Leukel, Dilja Krueger-Burg, Dilja Krueger-Burg, Clemens J. Sommer, Clemens J. Sommer, Michael J. Schmeisser, Michael J. Schmeisser   +9 more
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Ionotropic receptors mediate nitrogenous waste avoidance in Drosophila melanogaster

Communications Biology, 2021
Dhakal et al. use chemoreceptor screening on three ionotropic receptors in Drosophila, IR25a, IR76b, IR51b to evaluate their impact on avoidance behaviors against nitrogenous waste products.
Subash Dhakal, Jiun Sang, Binod Aryal, Youngseok Lee   +3 more
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Tripartite signalling by NMDA receptors

Molecular Brain, 2020
N-methyl-d-aspartate receptors (NMDARs) are excitatory glutamatergic receptors that are fundamental for many neuronal processes, including synaptic plasticity.
Vishaal Rajani, Ameet S. Sengar, Michael W. Salter   +2 more
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Retromer in Synaptic Function and Pathology

Frontiers in Synaptic Neuroscience, 2018
The retromer complex mediates export of select transmembrane proteins from endosomes to the trans-Golgi network (TGN) or to the plasma membrane. Dysfunction of retromer has been linked with slowly progressing neurodegenerative disorders, including ...
Lennart Brodin, Oleg Shupliakov, Oleg Shupliakov   +2 more
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GRIA3 p.Met661Thr variant in a female with developmental epileptic encephalopathy

Human Genome Variation, 2023
The X-linked human glutamate receptor subunit 3 (GRIA3) gene (MIM *305915, Xq25) encodes ionotropic α amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)-type glutamate receptor subunit 3, which mediates postsynaptic neurotransmission.
Satomi Okano, Yoshio Makita, Akie Miyamoto, Genya Taketazu, Kayano Kimura, Ikue Fukuda, Hajime Tanaka, Kumiko Yanagi, Tadashi Kaname   +8 more
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Identification and expression analysis of chemosensory receptors in the tarsi of fall armyworm, Spodoptera frugiperda (J. E. Smith)

Frontiers in Physiology, 2023
Chemosensation of tarsi provides moths with the ability to detect chemical signals which are important for food recognition. However, molecular mechanisms underlying the chemosensory roles of tarsi are still unknown.
Jun-Feng Dong, Hai-Bo Yang, Ding-Xu Li, Hong-Qi Yu, Cai-Hong Tian   +4 more
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Genome-Wide Characterization of Four Gastropod Species Ionotropic Receptors Reveals Diet-Linked Evolutionary Patterns of Functional Divergence

Animals
Ionotropic receptors (IRs) are a divergent subfamily of ionotropic glutamate receptors (iGluRs) that detect olfactory and environmental cues, influencing behaviors such as foraging and adaptation.
Gang Wang, Yi-Qi Sun, Fang Wang, Zhi-Yong Wang, Ni-Ying Sun, Meng-Jun Wei, Yu-Tong Shen, Yi-Jia Li, Quan-Qing Sun, Yushinta Fujaya, Xun-Guang Bian, Wen-Qi Yang, Kianann Tan   +12 more
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Differential Regulation of Ionotropic Glutamate Receptors [PDF]

Biophysical Journal, 2007
Ionotropic glutamate receptors (iGluRs), a family of ligand-gated ion channels, are responsible for the majority of fast excitatory neurotransmission in the central nervous system. Within this family, different members serve distinct roles at glutamatergic synapses.
Stoll, Laura, Hall, James, Van Buren, Nick, Hall, Amanda, Knight, Lee, Morgan, Andy, Zuger, Sarah, Van Deusen, Halena, Gentile, Lisa   +8 more
openaire   +2 more sources