Results 31 to 40 of about 1,272,062 (259)
Release of ATP and glutamate in the nucleus tractus solitarii mediate pulmonary stretch receptor (Breuer-Hering) reflex pathway [PDF]
The Breuer-Hering inflation reflex is initiated by activation of the slowly adapting pulmonary stretch receptor afferents (SARs), which monosynaptically activate second-order relay neurones in the dorsal medullary nucleus of the solitary tract (NTS ...
Enrique Llaudet +13 more
core +1 more source
Insect odorant response sensitivity is tuned by metabotropically autoregulated olfactory receptors. [PDF]
Insects possess one of the most exquisitely sensitive olfactory systems in the animal kingdom, consisting of three different types of chemosensory receptors: ionotropic glutamate-like receptors (IRs), gustatory receptors (GRs) and odorant receptors (ORs).
Merid N Getahun +4 more
doaj +1 more source
High-Affinity Kainate Receptor Subunits Are Necessary for Ionotropic but Not Metabotropic Signaling [PDF]
SummaryKainate receptors signal through both ionotropic and metabotropic pathways. The high-affinity subunits, GluK4 and GluK5, are unique among the five receptor subunits, as they do not form homomeric receptors but modify the properties of heteromeric ...
Russell, Theron A. +7 more
core +1 more source
Insects’ olfactory receptor plays a central role in detecting chemosensory information from the environment. Odorant receptors (ORs) and ionotropic receptors (IRs) are two types of olfactory receptors, and they are essential for the recognition of ...
Jia-Li Qian +8 more
doaj +1 more source
Undifferentiated embryonic stem cells express ionotropic glutamate receptor mRNAs
Ionotropic glutamate receptors (iGluRs) do not only mediate the majority of excitatory neurotransmission in the vertebrate CNS, but also modulate pre- and postnatal neurogenesis.
Svenja ePachernegg +31 more
doaj +1 more source
Identification of functional ionotropic glutamate receptor proteins in pancreatic β-cells and in islets of Langerhans [PDF]
The presence of ionotropic glutamate receptor proteins in islets of Langerhans and pancreatic β-cell lines (MIN6, HIT T15, RINm5F) was investigated. For this purpose immunoblot analysis of β-cell membranes was performed with subunit-specific antibodies ...
Ashcroft, Stephen J.H. +5 more
core +1 more source
Tuning Insect Odorant Receptors
Among the insect olfactory receptors the odorant receptors (ORs) evolved in parallel to the onset of insect flight. A special property of this receptor type is the capability to adjust sensitivity of odor detection according to previous odor contacts ...
Dieter Wicher
doaj +1 more source
Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte +6 more
wiley +1 more source
Structural Dynamics and Allosteric Signaling in Ionotropic Glutamate Receptors [PDF]
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that mediate excitatory neurotransmission events in the central nervous system. All distinct classes of iGluRs (AMPA, NMDA, Kainate) are composed of an N-terminal domain (NTD) and a ...
Dutta, Anindita
core
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source

