Odorant Binding and Conformational Dynamics in the Odorant-binding Protein [PDF]
In mammals, the olfactory epithelium secretes odorant-binding proteins (OBPs), which are lipocalins found freely dissolved in the mucus layer protecting the olfactory neurons. OBPs may act as passive transporters of predominantly hydrophobic odorant molecules across the aqueous mucus layer, or they may play a more active role in which the olfactory ...
Hajjar, Eric +4 more
openaire +5 more sources
DyBOBS: A Dynamic Biomimetic Assay for Odorant-Binding to Odor-Binding Protein
An in vitro system was developed to mimic the structural and flow conditions of the human olfactory epithelium and to measure the dynamics of odorant-binding to odor-binding protein (OBP). A hydrophilic fused silica capillary, coated internally with a thin (about 1.3 µm) aqueous film of recombinant rat-OBP3 mimicked the human olfactory epithelium ...
Yabuki, Masayuki +4 more
openaire +3 more sources
Organization and function of Drosophila odorant binding proteins
Odorant binding proteins (Obps) are remarkable in their number, diversity, and abundance, yet their role in olfactory coding remains unclear. They are widely believed to be required for transporting hydrophobic odorants through an aqueous lymph to ...
Nikki K Larter +2 more
doaj +3 more sources
Proteome response of Tribolium castaneum larvae to Bacillus thuringiensis toxin producing strains. [PDF]
Susceptibility of Tribolium castaneum (Tc) larvae was determined against spore-crystal mixtures of five coleopteran specific and one lepidopteran specific Bacillus thuringiensis Cry toxin producing strains and those containing the structurally unrelated ...
Estefanía Contreras +2 more
doaj +1 more source
Operating mechanism and molecular dynamics of pheromone-binding protein ASP1 as influenced by pH. [PDF]
Odorant binding protein (OBP) is a vital component of the olfactory sensation system. It performs the specific role of ferrying odorant molecules to odorant receptors.
Lei Han +6 more
doaj +1 more source
Kinetics of Odorant Recognition with a Graphene-Based Olfactory Receptor Mimicry
Malaria vector mosquito species rely on a handful of specific pheromones for mating; one of them, sulcatone (6-methyl-5-hepten-2-one), is also found in human exudation.
Caroline Bonazza, Klaus Bonazza
doaj +1 more source
Odorant Binding and Conformational Changes of a Rat Odorant-binding Protein [PDF]
Odorant-binding proteins (OBPs) are lipocalins secreted in the nasal mucus of vertebrates, which convey odorants to their neuronal receptors. We compared the binding properties of a recombinant rat OBP (OBP-1F) using a set of six odorants of various chemical structures.
Nespoulous, Claude +4 more
openaire +3 more sources
Pea aphid odorant-binding protein ApisOBP6 discriminates between aphid sex pheromone components, aphid alarm pheromone and a host plant volatile [PDF]
Olfactory perception of pheromones in insects involves odorant-binding proteins (OBPs), relatively small proteins (ca.110-240 amino acid residues) that can bind reversibly to behaviourally active olfactory ligands.
Sims, C. +16 more
core +1 more source
Odorant-binding protein expression in dMPPEDKO flies.
Odorant-binding protein expression in dMPPEDKO flies.
Deepthi Mahishi (6494951) +7 more
core +1 more source
How Far Does a Receptor Influence Vibrational Properties of an Odorant? [PDF]
The biophysical mechanism of the sense of smell, or olfaction, is still highly debated. The mainstream explanation argues for a shape-based recognition of odorant molecules by olfactory receptors, while recent investigations suggest the primary olfactory
Anna Reese +3 more
doaj +1 more source

