Biological Roles of Lipocalins in Chemical Communication, Reproduction, and Regulation of Microbiota
Frontiers in Physiology, 2021 Major evolutionary transitions were always accompanied by genetic remodelling of phenotypic traits. For example, the vertebrate transition from water to land was accompanied by rapid evolution of olfactory receptors and by the expansion of genes encoding
Romana Stopková +4 more
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Odorant Binding and Conformational Dynamics in the Odorant-binding Protein [PDF]
Journal of Biological Chemistry, 2006 In mammals, the olfactory epithelium secretes odorant-binding proteins (OBPs), which are lipocalins found freely dissolved in the mucus layer protecting the olfactory neurons. OBPs may act as passive transporters of predominantly hydrophobic odorant molecules across the aqueous mucus layer, or they may play a more active role in which the olfactory ...
Hajjar, Eric +4 more
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Proteome response of Tribolium castaneum larvae to Bacillus thuringiensis toxin producing strains. [PDF]
PLoS ONE, 2013 Susceptibility of Tribolium castaneum (Tc) larvae was determined against spore-crystal mixtures of five coleopteran specific and one lepidopteran specific Bacillus thuringiensis Cry toxin producing strains and those containing the structurally unrelated ...
Estefanía Contreras +2 more
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Operating mechanism and molecular dynamics of pheromone-binding protein ASP1 as influenced by pH. [PDF]
PLoS ONE, 2014 Odorant binding protein (OBP) is a vital component of the olfactory sensation system. It performs the specific role of ferrying odorant molecules to odorant receptors.
Lei Han +6 more
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Kinetics of Odorant Recognition with a Graphene-Based Olfactory Receptor Mimicry
Chemosensors, 2022 Malaria vector mosquito species rely on a handful of specific pheromones for mating; one of them, sulcatone (6-methyl-5-hepten-2-one), is also found in human exudation.
Caroline Bonazza, Klaus Bonazza
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Odorant Binding and Conformational Changes of a Rat Odorant-binding Protein [PDF]
Chemical Senses, 2004 Odorant-binding proteins (OBPs) are lipocalins secreted in the nasal mucus of vertebrates, which convey odorants to their neuronal receptors. We compared the binding properties of a recombinant rat OBP (OBP-1F) using a set of six odorants of various chemical structures.
Nespoulous, Claude +4 more
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How Far Does a Receptor Influence Vibrational Properties of an Odorant? [PDF]
PLoS ONE, 2016 The biophysical mechanism of the sense of smell, or olfaction, is still highly debated. The mainstream explanation argues for a shape-based recognition of odorant molecules by olfactory receptors, while recent investigations suggest the primary olfactory
Anna Reese +3 more
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Functional analysis of general odorant binding protein 2 from the meadow moth, Loxostege sticticalis L. (Lepidoptera: Pyralidae). [PDF]
PLoS ONE, 2012 Odorant binding proteins play a crucial role in transporting semiochemicals across the sensillum lymph to olfactory receptors within the insect antennal sensilla.
Jiao Yin +5 more
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Biotechnological applications of mammalian odorant-binding proteins [PDF]
Critical Reviews in Biotechnology, 2021 The olfactory system of mammals allows the detection and discrimination of thousands of odors from the environment. In mammals, odorant-binding proteins (OBPs) are considered responsible to carry odorant molecules across the aqueous nasal mucus to the olfactory receptors (ORs).
Filipa Gonçalves +3 more
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BMC Bioinformatics, 2007 Background Odorant binding proteins (OBPs) are believed to shuttle odorants from the environment to the underlying odorant receptors, for which they could potentially serve as odorant presenters.
Suganthan PN +4 more
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