Results 141 to 150 of about 9,310 (182)
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Molecular cloning of putative odorant-binding and odorant-metabolizing proteins
Biochemistry, 1991Olfactory reception occurs via the interaction of odorants with the chemosensory cilia of the olfactory receptor cells located in the nasal epithelium. The cDNA clones from mRNA specific to olfactory mucosa were studied. One of these clones, OBPII, encodes a secretory protein with significant homology to odorant-binding protein (OBP), a protein with ...
T N, Dear, K, Campbell, T H, Rabbitts
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Immunocytochemistry of Odorant-Binding Proteins
1994Odorant-binding proteins are small water-soluble proteins that have been detected in the perireceptor compartment of olfactory receptor cells of vertebrates and insects [1,2]. Although their definite physiological role in olfaction is still unclear, similar functions have been proposed in stimulus transport or inactivation [1–6].
Steinbrecht, R. +3 more
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Odorant binding initially occurring at the central pocket in bovine odorant-binding protein
Biochemical and Biophysical Research Communications, 2005Why bovine odorant-binding protein (OBPb), among OBP family, assumes a dimeric structure has been unclear. Here we clarified, by measuring the fluorescence of intrinsic tryptophan and tyrosine residues of intact OBPb and OBPb whose C-terminal 10 amino acids were deleted, that odorant enters the central pocket formed by the dimerization when OBPb first ...
Mineo, Ikematsu +2 more
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Odorant‐Binding Proteins: Expression and Function
Annals of the New York Academy of Sciences, 1998ABSTRACT: Odorant‐binding proteins (OBPs) are a major constituent of the aqueous perireceptor compartment in vertebrates and in insects. Although different in primary structure, they are supposed to serve similar functions in both animal groups: (i) OBPs may act as solubilizers and carriers of the lipophilic odorants in the aqueous mucus or sensillum ...
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Site-directed mutagenesis of odorant-binding proteins
2020Modifying the affinity of odorant-binding proteins (OBPs) to small ligands by replacement of specific residues in the binding pocket may lead to several technological applications. Thanks to their compact and stable structures, OBPs are currently regarded as the best candidates to be used in biosensing elements for odorants and volatiles detection. The
Jiao, Zhu +4 more
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Odorant-Binding Proteins from a Primitive Termite
Journal of Chemical Ecology, 2002Hitherto, odorant-binding proteins (OBPs) have been identified from insects belonging to more highly evolved insect orders (Lepidoptera, Coleoptera, Diptera, Hymenoptera, and Hemiptera), whereas only chemosensory proteins have been identified from more primitive species, such as orthopteran and phasmid species.
Yuko, Ishida +3 more
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Conformational Isomers of Insect Odorant-Binding Proteins
Archives of Biochemistry and Biophysics, 2002We have identified and cloned the cDNAs encoding odorant-binding proteins (OBPs) from the large black chafer, Holotrichia parallela, and the yellowish elongate chafer, Heptophylla picea. Each species possess two OBPs, the proteins migrating faster in native gels (OBP1) showed high amino acid identity (>88%) to previously identified pheromone-binding ...
Zhang, Deyu, Walter Soares, Leal
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Mechanistic events underlying odorant binding protein chemoreception
Proteins: Structure, Function, and Bioinformatics, 2007AbstractOdorant binding proteins (OBP's) are small hydrophilic proteins, belonging to the lipocalin family dedicated to bind and transport small hydrophobic ligands. Despite many works, the mechanism of ligand binding, together with the functional role of these proteins remains a topic of debate and little is known at the atomic level. The present work
Golebiowski, Jérôme +3 more
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Conformational Stability and Binding Properties of Porcine Odorant Binding Protein
Biochemistry, 1999Apparently homogeneous odorant binding protein purified from pig nasal mucosa (pOBP) exhibited subunit molecular masses of 17 223, 17 447, and 17 689 (major component) Da as estimated by ESI/MS. According to gel filtration, this protein, its truncated forms, and/or its variants are homodimeric under physiologic conditions (pH 6-7, 0.1 M NaCl).
Burova, T.V. +3 more
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Novel canine odorant binding proteins
2022La présente invention concerne l'utilisation d'une séquence choisie parmi Seq ID No 3, Seq ID No 1, Seq ID No 2, Seq ID No 4, Seq ID No 5, Seq ID No 6, Seq ID No 7, Seq ID No 8, et des variants fonctionnels correspondants, en tant que protéine de liaison odorante (OBP).
Glaz, Margot +4 more
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