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Biotechnological applications of mammalian odorant-binding proteins [PDF]

Critical Reviews in Biotechnology, 2021
The olfactory system of mammals allows the detection and discrimination of thousands of odors from the environment. In mammals, odorant-binding proteins (OBPs) are considered responsible to carry odorant molecules across the aqueous nasal mucus to the olfactory receptors (ORs).
Filipa Gonçalves, Artur Ribeiro, Carla Silva, Artur Cavaco-Paulo   +3 more
openaire   +4 more sources

Odorant Binding Causes Cytoskeletal Rearrangement, Leading to Detectable Changes in Endothelial and Epithelial Barrier Function and Micromotion

Biosensors, 2023
Non-olfactory cells have excellent biosensor potential because they express functional olfactory receptors (ORs) and are non-neuronal cells that are easy to culture.
Theresa M. Curtis, Annabella M. Nilon, Anthony J. Greenberg, Matthew Besner, Jacob J. Scibek, Jennifer A. Nichols, Janet L. Huie   +6 more
doaj   +1 more source

Enantiomeric Discrimination in Insects: The Role of OBPs and ORs

Insects, 2022
Olfaction is a complex recognition process that is critical for chemical communication in insects. Though some insect species are capable of discrimination between compounds that are structurally similar, little is understood about how this high level of
Cassie Sims, Michael A. Birkett, David M. Withall   +2 more
doaj   +1 more source

Structure, Binding Characteristics, and 3D Model Prediction of a Newly Identified Odorant-Binding Protein from the Cotton Bollworm, Helicoverpa armigera (Hübner)

Journal of Integrative Agriculture, 2012
The full-length sequence of the odorant binding protein 5 gene, HarmOBP5, was obtained from an antennae cDNA library of cotton bollworm, Helicoverpa armigera (Hübner). The cDNA contains a 444 bp open reading frame, encoding a protein with 147 amino acids,
Tian-tao ZHANG, Wei-xuan WANG, Shao-hua GU, Zi-ding ZHANG, Kong-ming WU, Yong-jun ZHANG, Yu-yuan GUO   +6 more
doaj   +1 more source

Biosensors for Odor Detection: A Review

Biosensors, 2023
Animals can easily detect hundreds of thousands of odors in the environment with high sensitivity and selectivity. With the progress of biological olfactory research, scientists have extracted multiple biomaterials and integrated them with different ...
Hongchao Deng, Takamichi Nakamoto
doaj   +1 more source

Axonal Odorant Receptors Mediate Axon Targeting

Cell Reports, 2019
Summary: In mammals, odorant receptors not only detect odors but also define the target in the olfactory bulb, where sensory neurons project to give rise to the sensory map.
Ilaria Zamparo, Simona Francia, Sira Angela Franchi, Nelly Redolfi, Elisa Costanzi, Axelle Kerstens, Yosuke Fukutani, Roberto Battistutta, Patrizia Polverino de Laureto, Sebastian Munck, Bart De Strooper, Hiroaki Matsunami, Claudia Lodovichi   +12 more
doaj   +1 more source

Interpopulational Variations of Odorant-Binding Protein Expression in the Black Cutworm Moth, Agrotis ipsilon

Insects, 2020
A long-range migrant species of moth (Agrotis ipsilon) has served as a model to compare the expression profiles of antennal proteins between different continental populations.
Jean-François Picimbon
doaj   +1 more source

The Odorant-Binding Protein Gene obp11 Shows Different Spatiotemporal Roles in the Olfactory System of Apis mellifera ligustica and Apis cerana cerana

Sociobiology, 2014
Odorant-binding proteins participate in the olfactory system of the honeybee. Apis mellifera ligustica and Apis cerana cerana are species of honeybee that have different biologic functions.
Hongxia Zhao, Yuexiong Luo, Jianghong Lee, Xuefeng Zhang, qin Liang, Xinnian Zeng   +5 more
doaj   +1 more source

Sex- and tissue-specific transcriptome analyses and expression profiling of olfactory-related genes in Ceracris nigricornis Walker (Orthoptera: Acrididae)

BMC Genomics, 2019
Background The sophisticated insect olfactory system plays an important role in recognizing external odors and enabling insects to adapt to environment.
Hao Yuan, Huihui Chang, Lina Zhao, Chao Yang, Yuan Huang   +4 more
doaj   +1 more source

An Expanded Survey of the Moth PBP/GOBP Clade in Bombyx mori: New Insight into Expression and Functional Roles

Frontiers in Physiology, 2021
We studied the expression profile and ontogeny (from the egg stage through the larval stages and pupal stages, to the elderly adult age) of four OBPs from the silkworm moth Bombyx mori.
Xia Guo, Ning Xuan, Guoxia Liu, Hongyan Xie, Qinian Lou, Philippe Arnaud, Bernard Offmann, Jean-François Picimbon, Jean-François Picimbon   +8 more
doaj   +1 more source