Results 191 to 200 of about 1,252,084 (241)

Role of iRhom2 in Olfaction: Implications for Odorant Receptor Regulation and Activity-Dependent Adaptation. [PDF]

open access: yesInt J Mol Sci
Azzopardi SA   +6 more
europepmc   +1 more source

Vertebrate odorant receptors

Cellular and Molecular Life Sciences (CMLS), 1999
Olfactory transduction begins with the binding of an odorous molecule to a protein receptor--odorant receptor--on the cell surface of olfactory neuron. Odorant receptors are encoded by a large gene family belonging to the superfamily of G-protein-coupled, seven-transmembrane-domain receptors. Since the identification of the receptor gene family in 1991,
H, Zhao, S, Firestein
openaire   +2 more sources

Evolution of odorant receptors

BioEssays, 2000
Odorant receptors (ORs) located in the nasal epithelium, at the ciliated surface of olfactory sensory neurons, represent the initial step of a transduction cascade that leads to odor detection. ORs form the largest and most diverse family of G-protein-coupled receptors (GPCRs).
openaire   +2 more sources

Cloning and expression of odorant receptors

Nature, 1993
Myriads of odorous molecules that vary widely in structure are nevertheless readily detected and discriminated by the sense of smell, but how this is achieved by the olfactory system has been a long-standing puzzle. Several different models have been proposed, and previous observations indicate that the recognition sites for odorous molecules could be ...
K, Raming   +6 more
openaire   +2 more sources

Ligand specificity of odorant receptors

Journal of Molecular Modeling, 2006
Odorant receptors belong to class A of the G protein-coupled receptors (GPCRs) and detect a large number of structurally diverse odorant molecules. A recent structural bioinformatic analysis suggests that structural features are conserved across class A of GPCRs in spite of their low sequence identity.
Khafizov, K.   +3 more
openaire   +4 more sources

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