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CRISPR‐mediated mutagenesis of the odorant receptor co‐receptor (Orco) gene disrupts olfaction‐mediated behaviors in Bactrocera dorsalis

Insect Science, 2022
Olfaction plays an essential role in insect behavior such as host location, foraging, mating, and oviposition. The odorant receptor co‐receptor (Orco) is an obligatory odorant receptor and indispensable in odor perception. Here, we characterized the Orco
Li Xu   +5 more
semanticscholar   +1 more source

Molecular mechanisms of caramel-like odorant-olfactory receptor interactions based on a computational chemistry approach.

Food Research International, 2023
Molecular mechanisms of caramel-like odorant-olfactory receptor interactions were investigated based on molecular docking and molecular dynamics simulations.
Shitong Zeng   +11 more
semanticscholar   +1 more source

Insect odorant receptor-based biosensors: Current status and prospects.

Biotechnology Advances, 2021
Whilst the senses of vision and hearing have been successfully automated and miniaturized in portable formats (e.g. smart phone), this is yet to be achieved with the sense of smell.
J. Cheema   +4 more
semanticscholar   +1 more source

Three host plant volatiles, hexanal, lauric acid and tetradecane, are detected by an antenna-biased expressed odorant receptor 27 in the dark black chafer Holotrichia parallela.

Journal of Agricultural and Food Chemistry, 2020
Insects rely on olfaction to locate their host plants by antenna in complex chemical environments. Odorant receptor (OR) genes are thought to play a crucial role in the process.
Xiao Wang   +6 more
semanticscholar   +1 more source

Vertebrate odorant receptors

Cellular and Molecular Life Sciences (CMLS), 1999
Olfactory transduction begins with the binding of an odorous molecule to a protein receptor--odorant receptor--on the cell surface of olfactory neuron. Odorant receptors are encoded by a large gene family belonging to the superfamily of G-protein-coupled, seven-transmembrane-domain receptors. Since the identification of the receptor gene family in 1991,
H, Zhao, S, Firestein
openaire   +2 more sources

Structural basis for odorant recognition of the insect odorant receptor OR-Orco heterocomplex

Science
Insects detect and discriminate a diverse array of chemicals using odorant receptors (ORs), which are ligand-gated ion channels comprising a divergent odorant-sensing OR and a conserved odorant receptor co-receptor (Orco).
Yidong Wang   +15 more
semanticscholar   +1 more source

Evolution of odorant receptors

BioEssays, 2000
Odorant receptors (ORs) located in the nasal epithelium, at the ciliated surface of olfactory sensory neurons, represent the initial step of a transduction cascade that leads to odor detection. ORs form the largest and most diverse family of G-protein-coupled receptors (GPCRs).
openaire   +2 more sources

Biosensing with Insect Odorant Receptor Nanodiscs and Carbon Nanotube Field-Effect Transistors.

ACS Applied Materials and Interfaces, 2019
Insect odorant receptors have been reconstituted into lipid nanodiscs and tethered to carbon nanotube field-effect transistors to function as a biosensor.
Thanihaichelvan Murugathas   +5 more
semanticscholar   +1 more source

Cloning and expression of odorant receptors

Nature, 1993
Myriads of odorous molecules that vary widely in structure are nevertheless readily detected and discriminated by the sense of smell, but how this is achieved by the olfactory system has been a long-standing puzzle. Several different models have been proposed, and previous observations indicate that the recognition sites for odorous molecules could be ...
K, Raming   +6 more
openaire   +2 more sources

INSECT ODOR AND TASTE RECEPTORS

Annual Review of Entomology, 2006
▪ Abstract  Insect odor and taste receptors are highly sensitive detectors of food, mates, and oviposition sites. Following the identification of the first insect odor and taste receptors in Drosophila melanogaster, these receptors were identified in a number of other insects, including the malaria vector mosquito Anopheles gambiae; the silk moth ...
Elissa A, Hallem   +2 more
openaire   +2 more sources

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