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Author Correction: Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors. [PDF]

Nat Commun
Pacalon J, Audic G, Magnat J, Philip M, Golebiowski J, Moreau CJ, Topin J.   +6 more
europepmc   +1 more source

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Structural basis for odorant recognition of the insect odorant receptor OR-Orco heterocomplex

Science
Insects detect and discriminate a diverse array of chemicals using odorant receptors (ORs), which are ligand-gated ion channels comprising a divergent odorant-sensing OR and a conserved odorant receptor co-receptor (Orco).
Yidong Wang, Liang Qiu, Bing Wang, Zeyuan Guan, Zhi Dong, Jie Zhang, Song Cao, Lulu Yang, Bo Wang, Zhou Gong, Liwei Zhang, Weihua Ma, Zhu Liu, Delin Zhang, Guirong Wang, Ping Yin   +15 more
semanticscholar   +3 more sources

Structural basis of amine odorant perception by a mammal olfactory receptor

Nature, 2023
Lu Guo, Jie Cheng, Shuo Lian, Qun Liu, Yan Lu, Yuan Zheng, Kongkai Zhu, Minghui Zhang, Yalei Kong, Chao Zhang, Naikang Rong, Yuming Zhuang, Guo-xing Fang, Jingjing Jiang, Tianyao Zhang, Xiang Han, Zili Liu, M. Xia, Shang-Gao Liu, Lei Zhang, S. Liberles, Xiao Yu, Yunfei Xu, Fan Yang, Qian Li, Jingfen Sun   +25 more
semanticscholar   +3 more sources

Structural basis of odor sensing by insect heteromeric odorant receptors

Science
Most insects, including human-targeting mosquitoes, detect odors through odorant-activated ion channel complexes consisting of a divergent odorant-binding subunit (OR) and a conserved co-receptor subunit (Orco).
Jiawei Zhao, A. Q. Chen, Jaewook Ryu, J. D. del Mármol   +3 more
semanticscholar   +3 more sources

CRISPR‐mediated mutagenesis of the odorant receptor co‐receptor (Orco) gene disrupts olfaction‐mediated behaviors in Bactrocera dorsalis

Insect Science, 2022
Olfaction plays an essential role in insect behavior such as host location, foraging, mating, and oviposition. The odorant receptor co‐receptor (Orco) is an obligatory odorant receptor and indispensable in odor perception. Here, we characterized the Orco
Li Xu, Hong-Bo Jiang, Kai-Yue Tang, Ying Yan, M. F. Schetelig, Jinjun Wang   +5 more
semanticscholar   +1 more source

Molecular mechanisms of caramel-like odorant-olfactory receptor interactions based on a computational chemistry approach.

Food Research International, 2023
Molecular mechanisms of caramel-like odorant-olfactory receptor interactions were investigated based on molecular docking and molecular dynamics simulations.
Shitong Zeng, Li-li Zhang, Peng Li, Dandan Pu, Yingjie Fu, Ruiyi Zheng, Hui Xi, Kaina Qiao, Dingzhong Wang, B. Sun, Shihao Sun, Yuyu Zhang   +11 more
semanticscholar   +1 more source

Insect odorant receptor-based biosensors: Current status and prospects.

Biotechnology Advances, 2021
Whilst the senses of vision and hearing have been successfully automated and miniaturized in portable formats (e.g. smart phone), this is yet to be achieved with the sense of smell.
J. Cheema, Colm Carraher, N. Plank, J. Travas-sejdic, A. Kralicek   +4 more
semanticscholar   +1 more source

Vertebrate odorant receptors

Cellular and Molecular Life Sciences (CMLS), 1999
Olfactory transduction begins with the binding of an odorous molecule to a protein receptor--odorant receptor--on the cell surface of olfactory neuron. Odorant receptors are encoded by a large gene family belonging to the superfamily of G-protein-coupled, seven-transmembrane-domain receptors. Since the identification of the receptor gene family in 1991,
H, Zhao, S, Firestein
openaire   +2 more sources

Three host plant volatiles, hexanal, lauric acid and tetradecane, are detected by an antenna-biased expressed odorant receptor 27 in the dark black chafer Holotrichia parallela.

Journal of Agricultural and Food Chemistry, 2020
Insects rely on olfaction to locate their host plants by antenna in complex chemical environments. Odorant receptor (OR) genes are thought to play a crucial role in the process.
Xiao Wang, Shang Wang, Jiankun Yi, Yunshuo Li, Jianan Liu, Jun Wang, J. Xi   +6 more
semanticscholar   +1 more source

Biosensing with Insect Odorant Receptor Nanodiscs and Carbon Nanotube Field-Effect Transistors.

ACS Applied Materials and Interfaces, 2019
Insect odorant receptors have been reconstituted into lipid nanodiscs and tethered to carbon nanotube field-effect transistors to function as a biosensor.
Thanihaichelvan Murugathas, H. Zheng, Damon Colbert, A. Kralicek, Colm Carraher, N. Plank   +5 more
semanticscholar   +1 more source