Results 21 to 30 of about 1,272,638 (236)
Nature Communications, 2016 Fulvestrant degrades the oestrogen receptor. Here, the authors report on a clinical trial using fulvestrant and show that mutations in the oestrogen receptor alpha gene are prevalent in circulating tumour DNA and do not influence the clinical outcome of ...
Jill M. Spoerke +15 more
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Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus
Acta Dermato-Venereologica, 2018 Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng +6 more
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Emerging Concepts of Apolipoprotein D with Possible Implications for Breast Cancer
Cellular Oncology, 2007 Apolipoprotein D (ApoD) is a small glycoprotein of 24 kD, and a member of the lipocalin family. ApoD exerts several intracellular mechanistic roles, especially ligand binding. Some putative ligands are arachidonic acid, progesterone, and tamoxifen.
Håvard Søiland +5 more
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Neurosignals, 2012 Oestrogen influences autonomic function via actions at classical nuclear oestrogen receptors α and β in the brain, and recent evidence suggests the orphan G protein-coupled receptor GPR30 may also function as a cytoplasmic oestrogen receptor.
Emma J. Spary +5 more
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Human Genomics, 2010 Breast cancer tumours among African Americans are usually more aggressive than those found in Caucasian populations. African-American patients with breast cancer also have higher mortality rates than Caucasian women. A better understanding of the disease
Pang Herbert +4 more
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GIT1 protects against breast cancer growth through negative regulation of Notch
Nature Communications, 2022 Notch signalling is reported to be hyperactivated in oestrogen receptor-negative (ER-) breast cancer. Here the authors show that G protein-coupled receptor kinase-interacting protein 1 (GIT1) negatively regulates Notch signalling and tumour growth in ER-
Songbai Zhang +16 more
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Investigation of hormone receptor expressions in the fins of Oryzias woworae (Actinopterygii: Beloniformes: Adrianichthyidae) [PDF]
Acta Ichthyologica et Piscatoria, 2014 Background. In the genus Oryzias, the morphology of the dorsal and anal fin constitute typical secondary sex characteristics that are controlled by sex steroid hormones through hormone receptors.
A. Ngamniyom, T. Sriyapai, P. Somyoonsap
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The role of oestrogen and progesterone receptors in gigantomastia
Archives of Medical Science, 2019 Introduction Gigantomastia is a rare condition characterised by excessive breast growth. The pathophysiology of mammary enlargement varies depending on the type of gigantomastia: gestational, juvenile virginal, or idiopathic. The study aimed at examining
Anna Kasielska-Trojan +4 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Relation between obesity and the oestrogen receptor status of breast cancer [PDF]
, 2014 Introduction: Obesity is a growing problem in the Western world. Correlations have been found between increasing body mass index (BMI) and breast cancer.
Pisani, David +2 more
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