Results 91 to 100 of about 1,357,177 (300)

Did the pile driving during the construction of the Offshore Wind Farm Egmond aan Zee, the Netherlands, impact porpoises? [PDF]

open access: yes
The Dutch consortium "NoordzeeWind" has built the first offshore wind farm in Dutch North Sea waters, known as "Offshore Wind farm Egmond aan Zee" (OWEZ) Part of the construction works consisted of driving 36 monopiles into the sea floor, during April ...
Camphuysen, C.J., Leopold, M.F.
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Current Research and Future Directions for Off-Site Construction through LangChain with a Large Language Model

open access: yesBuildings
Off-site construction is well-known technology that facilitates parallel processes of manufacturing and construction processes. This method enhances productivity while reducing accident, cost, and environmental impact.
Jaemin Jeong   +3 more
doaj   +1 more source

Analyzing the Potential of Hybrid and Electric Off-Road Equipment in Reducing Carbon Emissions from Construction Industries [PDF]

open access: yes, 2017
This report quantifies the likely impact recent improvements in emissions technology in the heavy construction equipment fleet will have on national and state-level carbon emissions from construction industries.
Holian, Matthew, Pyeon, Jae-Ho
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Industrialised Housing Delivery: A Systematic Literature Review and Thematic Synthesis of Uptake, Digital Integration, and P-DfMA Drivers

open access: yesBuildings
Industrialised construction (IC) represents a foundational strategy for overcoming entrenched productivity constraints and supply shortfalls in the housing sector.
Danesh Hedayati   +4 more
doaj   +1 more source

From Construction to Production: Enablers, Barriers and Opportunities for the Highways Supply Chain [PDF]

open access: yes, 2017
The report presents the initial findings of a project part of the Lean Collaborative Research at Highways England with academia that aims at understanding enablers, barriers and opportunities to transform the current highways construction supply chain ...
Gosling, Jonathan   +3 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Exploring the technology-organization-environment configurations to enhance stakeholder collaboration in the off-site construction projects

open access: yesJournal of Civil Engineering and Management
Stakeholder collaboration is critical in empowering off-site construction (OSC) projects to reduce the cost overrun, conflicts and quality problems.
Zezhou Wu   +5 more
doaj   +1 more source

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