Results 111 to 120 of about 1,357,177 (300)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Mitigation of Greenhouse Gas Emissions from Urban Environmental Infrastructures [PDF]
, 2018 The world’s population will increase to 9.4 billion people by 2050 and 70% of whom will be living in urban areas. Such urbanization with population growth and industrial development demands in turn create a need for the planning, design, and construction
KIm, Jongkon +2 more
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Developments in the Built EnvironmentEffectively monitoring and analyzing on-site module installation for modular integrated construction (MiC) is essential to properly coordinating the MiC process.
Jongyeon Baek, Daeho Kim, Byungjoo Choi
doaj +1 more source
Developing an uncertainty analysis model for off-site building production [PDF]
The hybrid use of off-site and on-site processes in construction projects has increased significantly over the past decade. The analysis and management of uncertainty in hybrid projects is not a trivial task as workflow variability in off-site and on ...
Arashpour, M, Wakefield, R
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Construction in Imperial Rome: organisation, logistics, and daily life on building sites
Arqueología de la ArquitecturaThis article investigates the phenomenon of the building site in ancient Rome, drawing on ancient literary sources, legal texts, as well as epigraphic, iconographic, and archaeological evidence.
Fabrizio Sommaini
doaj +1 more source
Revisiting the Three Peculiarities of Production in Construction [PDF]
Compared to many other industries, construction is a specific type of project industry with certain pe- culiarities influencing the characteristics of constructed products, ways of production, and the indus- try itself.
Koskela, Lauri, Vrijhoef, Ruben
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source