Results 121 to 130 of about 7,149,350 (256)

Integrated Maturity Assessment of Manufacturing, Logistics, and Assembly in Off-Site Construction

open access: yesBuildings
Off-site construction (OSC) is recognized for its potential to improve productivity, quality, safety, and sustainability. However, these benefits are often not fully realized because manufacturing principles and their effects on subsequent stages remain ...
Jesús Ortega   +3 more
doaj   +1 more source

Net-Zero and Digitalisation in Off-Site Construction

open access: yes
The UK Government set targets to achieve net-zero buildings by 2050. Consequently, there is a need for off-site construction companies to achieve net-zero over the coming years.
Collington, Nick   +9 more
core   +1 more source

Construction planning workbench [PDF]

open access: yes, 2004
This report is an attempt to present the current state of product and process modelling in the building industry in general, and in construction planning and scheduling in particular.

core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Off-target site analysis.

open access: yes, 2018
(A) The target site (T) and ten predicted off-target sites (OT) for sgRNA91/Cas9. OT1~OT10 represents 10 potential off-target sites, and T represents target site.
Hongming Yuan (2200930)   +20 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

A Perception Survey of Lean Management Practices for Safer Off-Site Construction

open access: yesBuildings
Lean practice is recognised for having a great potential in promoting safety risk management in off-site construction (OSC). This paper presents results of a study conducted to assess the impact of lean practice on safety risk management in OSC in a ...
Wakisa Simukonda, Fidelis Emuze
doaj   +1 more source

Adoption in the construction industry [PDF]

open access: yes, 2006
This report draws together the key findings from six case studies on the subject of ebusiness\ud Adoption in Construction conducted in Australia by the University of Newcastle\ud (UON) and Royal Melbourne Institute of Technology (RMIT) from 2005 through ...

core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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