Results 131 to 140 of about 156,415 (259)

Success criteria comparison of eight implemented projects to improve the planning, design, and construction of floodplain wetlands. [PDF]

PLOS Water
Hawley RJ, Nietch C, Knight D, Acosta S, Cooper K, Korth N, Raetz A, McManus J, McClatchy R, Hahn J, Lubbers H, Lair L, Winston RJ.   +12 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Deep learning-driven prediction of on-target activity, off-target risk, and repair outcomes in CRISPR/Cas9: current landscape and multi-scale perspectives. [PDF]

J Transl Med
Du W, Zhang T, Guo L, Zheng Y, Zhang H, Zhu X, Tang D, Hu H, Chen L, Liu C.   +9 more
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Unlocking the Potential for Genetic Engineering of the Straw-Degrading Mushroom <i>Stropharia rugosoannulata</i> by Constructing a CRISPR/Cas9 Gene Editing System. [PDF]

J Fungi (Basel)
Hao H, Song S, Wang Q, Tong Z, Xu W, Yang J, Yue Y, Xiao T, Zhang Y, Zhang J, Chen H.   +10 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Using Prefabricated Wood Light-Frame in Multi-Storey and Non-Residential Construction Projects: Motivations and Barriers of Professionals in Quebec

BioResources
Despite prefabricated wood light-frame construction’s technical viability and ability to address labor shortages and industry productivity issues, its adoption remains limited.
Baptiste Giorgio, Pierre Blanchet, Aline Barlet, Adrien Gaudelas   +3 more
doaj  

Wirelessly controlled modular automatic chambers for greenhouse gas flux monitoring in natural and agricultural ecosystems. [PDF]

HardwareX
Mastepanov M.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source