Results 131 to 140 of about 1,357,177 (300)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A Perception Survey of Lean Management Practices for Safer Off-Site Construction
BuildingsLean practice is recognised for having a great potential in promoting safety risk management in off-site construction (OSC). This paper presents results of a study conducted to assess the impact of lean practice on safety risk management in OSC in a ...
Wakisa Simukonda, Fidelis Emuze
doaj +1 more source
Automatic generation of progress profiles for eathwork operations using 4D visualisation model [PDF]
Despite of the advances in construction planning and scheduling software, construction managers and planners are still facing problems in achieving accurate planning, scheduling and costing due to the one-off nature of the construction projects and the ...
Castro, S, Dawood, N, Shah, RK
core
Green Housing = Improved Health: A Winning Combination [PDF]
, 2011 The case studies in this paper explore the relationship between housing and health. It explains how building affordable green housing provides health benefits to low-income residentsand it identifies the benefits of green housing for the environment and ...
Noreen Beatley
core
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Modular assembly with postponement to improve health, safety & productivity in construction [PDF]
, 2009 This paper presents the outcome of an engineering study as part of the design and development of a lean and agile construction system and in particular its supply chain component.
Bower, D +3 more
core
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Proactive Production Scheduling Approach for Off-Site Construction with Due Date Uncertainty
Applied SciencesThis study proposes a robust precast concrete (PC) production scheduling model for PC construction projects with schedule uncertainty by adopting a proactive scheduling approach.
Taehoon Kim, Yong-Woo Kim
doaj +1 more source