Results 101 to 110 of about 1,357,177 (300)

Alaska Correctional Requirements: A Forecast of Prison Population through the Year 2000 — Executive Summary [PDF]

open access: yes, 1986
This report is part of the Fire Island Prison Feasibility Study, a project conducted jointly by the School of Justice and School of Engineering at University of Alaska, Anchorage under contract to the Alaska Department of Corrections.
UAA School of Justice
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

The visual, the accidental and the actual in the historiography of the fort of Shinkakasa, Democratic Republic of Congo, 1891- 1909 [PDF]

open access: yes, 2019
Much against the advice of his military counsellors about static fortifications being obsolete in an age and continent of gunboat diplomacy, the Belgian king Leopold II took a resolute stand.
Bekers, Willem, Fivez, Robby
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Integrating Building Information Modeling with Logistic Chain: A Case Study of a Material Management System for Modular Construction

open access: yesBuildings
To continuously improve the efficiency of the construction project delivery process, various innovative methods and technologies have been developed and adopted in the past decades.
Lijun Liu   +3 more
doaj   +1 more source

Construction-Oriented Architectural Design in Off-Site Construction Towards Lean Construction and Management

open access: yes, 2022
The rapid development of Off-site Construction (OSC) has closely linked it to Lean Construction (LC). The importance of design has been highlighted in LC as the primary means to produce value to clients. However, the adoption of lean thinking is still modest in design.
openaire   +1 more source

Oyster Reef Restoration Project for the City of Dover, Grizzle [PDF]

open access: yes, 2006
This project was conducted as a contract between the City of Dover and the University of New Hampshire, with additional funding supplied by the New Hampshire Estuaries Project.
Abeels, Holly   +2 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Artificial reef plan for sport fish enhancement [PDF]

open access: yes, 1990
Hard bottom substrate provides habitat for a multitude of marine fishes, invertebrates, and plants - particularly giant kelp - which are of direct and indirect importance to sport and commercial fisheries.
Lewis, Robin D.   +2 more
core  

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