Results 101 to 110 of about 1,639,925 (354)

Fire Island Feasibility Study: Summary Report — Final Report [PDF]

open access: yes, 1986
This report is part of the Fire Island Prison Feasibility Study, a project conducted jointly by the School of Justice and School of Engineering at University of Alaska, Anchorage under contract to the Alaska Department of Corrections.
UAA School of Engineering   +1 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Analysis of directions for improving education and training system to foster offsite construction architectural professionals in South Korea

open access: yesJournal of Asian Architecture and Building Engineering
Recently, Off-Site Construction (OSC) which includes Precast Concrete, modular, and prefabricated construction has been expanding. This represents replacement of traditional construction, reduction in the construction site labor, and major change in the ...
W. G. Yun   +3 more
doaj   +1 more source

Analyzing the Potential of Hybrid and Electric Off-Road Equipment in Reducing Carbon Emissions from Construction Industries [PDF]

open access: yes, 2017
This report quantifies the likely impact recent improvements in emissions technology in the heavy construction equipment fleet will have on national and state-level carbon emissions from construction industries.
Holian, Matthew, Pyeon, Jae-Ho
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Integrated value model for sustainable assessment of school centers construction [PDF]

open access: yes, 2014
Hundreds of new school centers were built in Catalonia between 2000 and 2009. It was a governmental decision in order to solve an endemic lack of centers that in the early 2000s had worsen.
Aguado de Cea, Antonio   +1 more
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Did the pile driving during the construction of the Offshore Wind Farm Egmond aan Zee, the Netherlands, impact porpoises? [PDF]

open access: yes
The Dutch consortium "NoordzeeWind" has built the first offshore wind farm in Dutch North Sea waters, known as "Offshore Wind farm Egmond aan Zee" (OWEZ) Part of the construction works consisted of driving 36 monopiles into the sea floor, during April ...
Camphuysen, C.J., Leopold, M.F.
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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