Results 131 to 140 of about 1,639,925 (354)

Revisiting the Three Peculiarities of Production in Construction [PDF]

open access: yes
Compared to many other industries, construction is a specific type of project industry with certain pe- culiarities influencing the characteristics of constructed products, ways of production, and the indus- try itself.
Koskela, Lauri, Vrijhoef, Ruben
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Construction in Imperial Rome: organisation, logistics, and daily life on building sites

open access: yesArqueología de la Arquitectura
This article investigates the phenomenon of the building site in ancient Rome, drawing on ancient literary sources, legal texts, as well as epigraphic, iconographic, and archaeological evidence.
Fabrizio Sommaini
doaj   +1 more source

Comparative Assessment of the Carbon Footprint of on-site and off-site Wall Element Constructions

open access: diamond, 2023
Selamawit Mamo Fufa   +3 more
openalex   +1 more source

Construction and Demolition Waste Reduction: Yannell Residence, Chicago IL [PDF]

open access: yes, 2009
This case study is one in a series developed by the Illinois Sustainable Technology Center to highlight techniques for saving money and protecting the environment through reuse and recycling of construction and demolition debris.

core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

NaturWall©: facciate in legno multifunzionali per la riqualificazione del patrimonio edilizio / NaturWall©:multifunctional wood façade in existent building refurbishment [PDF]

open access: yes, 2012
Naturwall© is a research conducted by Politecnico of Turin (DAD) (under supervision of Prof.G.Callegari) and a local PMI support (Natural House, Castellamonte), promoted by Giovanni Goria Foundation "Master dei Talenti" programme.
Spinelli, Antonio
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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